The most common signs and symptoms of heart failure are:
All of these symptoms are the result of fluid buildup in your body. When symptoms start, you may feel tired and short of breath after routine physical effort, like climbing stairs.
As your heart grows weaker, symptoms get worse. You may begin to feel tired and short of breath after getting dressed or walking across the room. Some people have shortness of breath while lying flat.
Fluid buildup from heart failure also causes weight gain, frequent urination, and a cough that's worse at night and when you're lying down. This cough may be a sign of acute pulmonary edema (e-DE-ma). This is a condition in which too much fluid builds up in your lungs. The condition requires emergency treatment.

The image shows the major signs and symptoms of heart failure.
Interested in learning more about heart disease in women? View a Storify archive of a September 28, 2012, Twitter chat on women’s heart health. The discussion includes experts from The Heart Truth®, Million Hearts™, healthfinder.gov, and the American College of Cardiology’s CardioSmart™
Clinical trials are research studies that explore whether a medical strategy, treatment, or device is safe and effective for humans. To find clinical trials that are currently underway for Heart Failure, visit www.clinicaltrials.gov.
November 5, 2012
Therapy with bone marrow-derived stem cells does not improve short-term recovery after heart attack
Administering to patients stem cells derived from their own bone marrow either three or seven days after a heart attack is safe but does not improve heart function six months later, according to a clinical trial supported by the National Institutes of Health.
The NHLBI updates Health Topics articles on a biennial cycle based on a thorough review of research findings and new literature. The articles also are updated as needed if important new research is published. The date on each Health Topics article reflects when the content was originally posted or last revised.