People at highest risk for excessive blood clotting have both acquired and genetic risk factors. For example, if you smoke and have the Factor V Leiden mutation and atherosclerosis, you're at higher risk than someone who has only one of these risk factors.
For more information about the diseases, conditions, and other factors that can lead to excessive blood clotting, go to "What Causes Excessive Blood Clotting?"
You're more likely to have a genetic cause of excessive blood clotting if you have:
Factor V Leiden is one of the most common genetic mutations that can alter the blood clotting process. This mutation accounts for 40–50 percent of genetic blood clotting disorders in Caucasians.
Another risk factor for excessive blood clotting is antiphospholipid antibody syndrome. APS is an autoimmune disorder that can trigger blood clots to form in the body's arteries and veins. These blood clots can lead to many health problems, including frequent miscarriages.
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