The National Heart, Lung, and Blood Institute (NHLBI) is strongly committed to supporting research aimed at preventing and treating heart, lung, and blood diseases and conditions and sleep disorders.
NHLBI-supported research has led to many advances in medical knowledge and care. However, many questions remain about various diseases and conditions, including angina.
The NHLBI continues to support research aimed at learning more about angina. For example, the NHLBI currently is sponsoring a study called PROMISE.
This study compares computed tomography angiography (CTA) with stress testing in patients who have suspected coronary heart disease (CHD). The goal of this study is to show whether initial screening with CTA can improve the outcomes for patients who have CHD.
Research often depends on the willingness of volunteers to take part in clinical trials. Clinical trials test new ways to prevent, diagnose, or treat various diseases and conditions.
For example, new treatments for a disease or condition (such as medicines, medical devices, surgeries, or procedures) are tested in volunteers who have the illness. Testing shows whether a treatment is safe and effective in humans before it is made available for widespread use.
By taking part in a clinical trial, you can gain access to new treatments before they’re widely available. You also will have the support of a team of health care providers, who will likely monitor your health closely. Even if you don’t directly benefit from the results of a clinical trial, the information gathered can help others and add to scientific knowledge.
If you volunteer for a clinical trial, the research will be explained to you in detail. You’ll learn about treatments and tests you may receive, and the benefits and risks they may pose. You’ll also be given a chance to ask questions about the research. This process is called informed consent.
If you agree to take part in the trial, you’ll be asked to sign an informed consent form. This form is not a contract. You have the right to withdraw from a study at any time, for any reason. Also, you have the right to learn about new risks or findings that emerge during the trial.
For more information about clinical trials related to angina, talk with your doctor. You also can visit the following Web sites to learn more about clinical research and to search for clinical trials:
Clinical trials are research studies that explore whether a medical strategy, treatment, or device is safe and effective for humans. To find clinical trials that are currently underway for Angina, visit www.clinicaltrials.gov.
March 10, 2013
NIH statement on the vitamin component of the Trial to Assess Chelation Therapy
Preliminary results from the vitamin component of the Trial to Assess Chelation Therapy (TACT) were released today during the American College of Cardiology’s 2013 Scientific Sessions. The study found that overall heart attack patients given a combination of high-dose oral vitamins and minerals did not exhibit a significant reduction in recurrent cardiac events over those who did not receive the high-dose vitamins and minerals.
The NHLBI updates Health Topics articles on a biennial cycle based on a thorough review of research findings and new literature. The articles also are updated as needed if important new research is published. The date on each Health Topics article reflects when the content was originally posted or last revised.