How Can Thrombotic Thrombocytopenic Purpura Be Prevented?

Both inherited and acquired thrombotic thrombocytopenic purpura (TTP) occur suddenly with no clear cause. You can't prevent either type.

If you've had TTP, it's important to watch for signs and symptoms of a relapse (flareup). (See "Living With Thrombotic Thrombocytopenic Purpura" for more information.)

Talk with your doctor about factors that may trigger TTP or a flareup, including:

• Some diseases or conditions, such as pregnancy, cancer, HIV, infections, or lupus.
• Some medical procedures, such as surgery and blood and marrow stem cell transplant.
• Some medicines, such as ticlopidine, clopidogrel, cyclosporine A, chemotherapy, and hormone replacement therapy and estrogens. If you take any of these medicines, your doctor may recommend a different medicine.
• Quinine, which is a substance often found in tonic water and nutritional health products.