Statement: Increased aerobic activity to increase cardiorespiratory
fitness favorably affects blood lipids, particularly if accompanied by weight
loss. Evidence Category A.
Rationale: Nine RCTs
testing the effects of weight loss on lipoproteins measured cardiorespiratory
fitness, as measured by maximal oxygen uptake (369, 375, 380, 384, 399, 401, 404-406).
Weight loss was accompanied by increased fitness if the intervention included
increased physical activity or physical activity combined with diet (375, 380, 401, 404-406). These studies
were not designed to test whether increased cardiorespiratory fitness reduces
blood lipids independent of weight loss in overweight and obese adults.
However, considerable evidence exists that aerobic exercise decreases
triglycerides and total cholesterol and may increase HDL-cholesterol in men and
women, particularly if accompanied by weight loss (411).
|Recommendation: Weight loss is recommended to lower
elevated levels of total cholesterol, LDL-cholesterol and triglycerides and to
raise low levels of HDL-cholesterol in overweight and obese persons with
dyslipidemia. Evidence Category A.