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Changes to the Guidelines

The EPR-3 was initially posted to the NHLBI website in August 2007. Periodically edits are made to this document and these edits are logged onto this change page.

As of August 5, 2008 the following edits have been made (specific wording changes are indicated in bold):

Page Figure or Table Changes
75 Figure 3-5a: Assessing Asthma Control in Children 0 - 4 Years of Age Under the heading Well Controlled, Nighttime awakenings - change to read:
"one time or less per month"
311 Figure 4-4a: Usual Dosages for Long-Term Control Medications in Children Under the heading, Systemic Corticosteroids, ages 0 to 4 years - change to read:
Short-course "burst": 1 - 2 mg/kg/day, maximum 60 mg/day for 3 - 10 days.
315 Figure 4-4b: Estimated Comparative Daily Dosages for Inhaled Corticosteroids in Children (continued) Under the first bullet, 3rd dash - replace text to read:
The doses for budesonide and fluticasone MDI or DPI are based on recently available comparative data. These new data, including meta-analyses, show that fluticasone requires one-half the microgram dose of budesonide DPI to achieve comparable efficacy (Adams et al. 2005; Barnes et al. 1998; Nielsen and Dahl 2000).
318 Figure 4-4c: Usual Dosages for Quick-Relief Medications in Children (continued) Under the heading, Systemic Corticosteroids, ages 5 - 11 years - change to read:
Short-course "burst": 1-2 mg/kg/day, maximum 60 mg/day for 3 - 10 days.
349 Figure 4-8b: Estimated Comarative Daily Dosages for Inhaled Corticosteroids for Youths 12 Years of Age or Older and Adults Under the last bullet, 3rd dash - replace text to read:
The doses for budesonide and fluticasone MDI or DPI are based on recently available comparative data. These new data, including meta-analyses, show that fluticasone requires one-half the microgram dose of budesonide DPI to achieve comparable efficacy (Adams et al. 2005; Barnes et al. 1998; Nielsen and Dahl 2000).
387 Figure 5-5: Dosages of Drugs for Asthma Exacerbations Under the heading, Anticholinergics, Ipratropium bromide nebulizer solution - change to read:
0.25 - 0.5 mg every 20 minutes for 3 doses, then as needed
387 Figure 5-5: Dosages of Drugs for Asthma Exacerbations Under the heading Anticholinergics, Iptratropium with albuterol nebulizer solution - change to read:
1.5 - 3.0 mL every 20 minutes for 3 doses, then as needed
387 Figure 5-5: Dosages of Drugs for Asthma Exacerbations Under the heading, Systemic Corticosteroids, Prednisone - change to read:
1 - 2 mg/kg in 2 divided doses (maximum = 60 mg/day) until PEF is 70% of predicted or personal best

Last updated: August 5, 2008

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