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Case Western Reserve University Pre and Post-doctoral Training Program in Biometric Genetic Analysis of Cardiopulmonary Disease
Grant #: T32 HL007567
Program Director: Xiaofeng Zhu, PhD,
Co-Director: Catherine Stein, PhD,
Contact: Marina Leydiker; Phone: 216-368-0201

Trainees Supported: Predoctoral Ph.D – 6 positions, Postdoctoral PhD or MD – 2 positions

Areas of Emphasis: Cardiovascular and pulmonary diseases, sleep and hypoxic response, hypertension, inflammation/infection, statistical genetics, genetic epidemiology, biostatistics, obesity, transcriptomics, proteomics, and metabolomics

Program Summary:

This program provides predoctoral and postdoctoral training specifically in the areas of statistical genetic analysis and genetic epidemiology, with applications to the study of risk factors for cardiovascular and pulmonary disease. After providing only postdoctoral training for the first seventeen years, the program was expanded in 2000 to provide both predoctoral and postdoctoral training and has continued to provide both types of training. Predoctoral training is for the Ph.D. degree in Epidemiology and Biostatistics with concentration in Genetic Epidemiology and Bioinformatics. The most important mode of training for postdoctoral students is that of conducting collaborative research with faculty: methodological research (using statistical modeling or computer simulations) and/or substantive research by means of data analysis, using a computer; in the latter case, there will be strong interaction with established research workers in the area of application. All trainees attend regularly scheduled seminars and certain lecture and/or reading courses, including mandatory lectures in bioethics.

A particular feature of the program is the presence of internationally known biostatisticians/geneticists/genetic epidemiologists as visitors, for periods of a few days to a week, giving seminars and short courses in their particular fields of specialty and talking to the trainees about their research projects.

In addition to the Program Leaders (Drs. Zhu and Stein), the other Primary Mentors are: Robert Elston, PhD (Professor of Epidemiology and Biostatistics), who initiated the program in 1984 and was until recently the Director, Sudha Iyengar, PhD (Professor of Epidemiology and Biostatistics); Jill Barnholtz-Sloan, PhD (Associate Professor, General Medical Science); Susan Redline MD, MPH (Professor of Medicine and Pediatrics); Mark Schluchter PhD (Professor of Epidemiology and Biostatistics); Robert Igo, PhD (Assistant Professor of Epidemiology and Biostatistics); Li Li, PhD (Professor of Epidemiology and Biostatistics, and Oncology), Jin Li, PhD (Professor of Computer Science), Nora Nock, PhD (Associate Professor of Epidemiology and Biostatistics) and Farren Briggs, PhD (Assistant Professor of Epidemiology and Biostatistics).

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Last updated: June 2014

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