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NHLBI Funding Guidelines are also updated periodically in the Dear Colleague letters. These are found in the Communications from the Director category.
Additional Extramural Policy Notices from the NIH Office of Extramural Research
Also see the Grants Policy and Guidance section of the NIH Home Page for additional information. This includes information on NHLBI and other NIH grants in the CRISP (Computer Retrieval of Information on Scientific Projects) and the NIH Guide to Grants and Contracts.