VITA: Vascular Interventions/Innovations and Therapeutic Advances

The objective of the VITA Program is to enable and accelerate the development of promising diagnostic and therapeutic modalities for certain diseases within the purview of the National Heart, Lung and Blood Institute (NHLBI).

The VITA Program will provide support for early-stage translational development of product candidates in the fields of vascular disorders, thrombotic diseases, and pulmonary hypertension. Proposed project areas of interest may include peripheral arterial disease, aortic aneurysms and dissections, pulmonary vascular disorders, venous and arterial thrombosis, thromboembolic disorders, and disorders of the lymphatic system. Diseases of the coronary and intracranial arteries are excluded from this program.

Product candidates, as it concerns the VITA Program, may include new diagnostics, new therapeutic interventions (agents or devices), or novel applications of existing therapeutic interventions. The product candidate(s) under study and development can include, but are not limited to: small molecules, small peptides, proteins or antibodies, devices, diagnostic tests, imaging probes, genetic markers, and cell or gene based therapeutic agents.

The VITA Program will use a broad agency announcement (BAA) to solicit proposals for the development projects and a Request For Proposals (RFP) to solicit proposals for a Program Coordinating Center (PCC). The primary objective of the PCC is to work with the investigative sites and the NHLBI to ensure that the funded development projects are on track to meet defined milestones along the translational pathway.

The BAA and RFP solicitations contain required information for submitting contract proposals for the VITA Program Contract proposals are due by 4 PM (EDT) on August 24, 2012.

To view the solicitations visit the following:

The VITA Program hosted a webinar on Thursday, June 21, 2012, to address Offerors’ questions regarding the Program, proposal preparation, and submission process.

Details regarding the content of the VITA webinar and answers to questions that were asked during the webinar have been posted via amendments to the two solicitations published on the FedBizOpps website. Offerors should review these amendments, which are accessible via these “Amendment” links:

BAA - of external link

RFP - of external link

Any questions may be sent to Cornelius Moore, Contracting Officer, NHLBI, National Institutes of Health, email address: NHLBIVITA@NHLBI.NIH.GOV. Offerors are encouraged to monitor the FedBizOpps website ( of external link) for other updates related to the VITA Program.

Last Updated July 2012

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