"Coronary Artery Disease Risk Development in Young Adults (CARDIA) Study--Computed Tomography Reading Center (CTRC)"
| AMENDMENT OF SOLICITATION NO.: | RFP-NHLBI-HC-98-36 |
| AMENDMENT NO.: | 1 |
| AMENDMENT DATE: | July 2, 1999 |
| RFP ISSUE DATE: | June 2, 1999 |
| ISSUED BY: | William M Stevens, Contracting Officer National Institutes of Health National Heart, Lung, and Blood Institute Contracts Operations Branch Rockledge Building, Room 6118 6701 Rockledge Drive, MSC 7902 Bethesda, Maryland 20892-7902 |
| NAME AND ADDRESS OF OFFERORS: | To all recipients of RFP No. NHLBI-HC-98-36 |
Paragraph A. subparagraph 5. is amended to read as follows:
5. Perform readings and information abstractions of CT measurements on approximately 3,152 studies during the pilot test and 12-month examination period.
[Note: It is expected that 3,890 CARDIA participants will undergo the Year 15 examination and that 80% (n=3,112) will undergo CT examinations during the 12-month examination period, from June 1, 2000 to May 31, 2001. Plan to reread 5% of all studies by a second reader (n=156) for quality control purposes. Plan for a pilot study to include approximately 10 studies per site with rereadings by the same and a second reader to estimate intra- and inter-reader variability. Thus, the number of pilot studies would be aproximately 40 (reader A) + 40 (reader A again) + 40 (reader B). Offerors are also free to propose alternative strategies for the pilot study.]
Please acknowledge receipt of amendment 1 (ONE) by including it with your original business proposal. The due date for receipt of proposals remains unchanged by this amendment.
Sincerely,
/s/
William M. Stevens
Contracting Officer
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