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Who will review my application and when?

Who will review my application and when?

Your clinical Grant 

Grant
financial assistance mechanism providing money, property, or both to an eligible entity to carry out an approved project or activity. A grant is used whenever the NIH 
National Institutes of Health (NIH)
the United State's medical research agency, a federal government agency composed of diverse Institutes and Centers that conduct and support biomedical and behavioral research. NIH Homepage.
Institute or Center anticipates no substantial programmatic involvement with the recipient during performance of the financially assisted activities.
Application ( GA 
Grant Application
An application for financial assistance from a Public Health Service agency to fund biomedical or behavioral research, using the paper PHS 
Public Health Service (PHS)
governmental division comprised of agencies related to health and human services such Agency for Healthcare Research and Quality (AHRQ), Centers for Medicare & Medicaid Services ( CMS ), Food and Drug Administration (FDA), and National Institutes of Health (NIH) to name a few. DHHS Homepage
398 or electronic SF 424 forms and instructions.
) is assigned for review to either CSR 
Center for Scientific Review (CSR)
the portal for NIH grant applications and their review for scientific merit. It organizes the peer review groups that evaluate the majority (70%) of the research grant applications sent to NIH. CSR Homepage
or to an NHLBI 
National Heart, Lung, Blood Institute (NHLBI)
a NIH Institute that provides leadership for a national program in diseases of the heart, lung, and blood as well as blood resources, sleep disorders and the Woman's Health Initiative. NHLBI Homepage.
Review group. CSR reviews most R01s, R21s, pre and postdoctoral fellowships, and small business applications. In 2005, the number of grants submitted to NIH grew to 73,000 with 52,000 of these being reviewed by CSR.  NHLBI review groups handle applications that have Institute-specific features such as program projects, training grants, career development awards, responses to Requests for Applications and some clinical studies. 

The Peer Review Process is an excellent CSR overview of the process for assignment and review of your application.  A short video called Inside the Grant Process (39 minutes) will help give you a glimpse into a study section meeting and the peer review process at NIH.  CSR presents Descriptions of the Integrated Review Groups, Study Sections and Small Business Activities to give applicants a better understanding of the organization and function of the review groups.

Multi-center clinical applications are assigned to an NHLBI review group, the Clinical Trials Review Committee (CLTR).  CLTR is a standing committee composed of experts in heart, lung and blood diseases with biostatisticians and ad hoc reviewers.  The review criteria and process is similar to CSR with the standard scoring system.  CLTR meets three times a year in February, June and October in which new AND amended applications are reviewed. 

Your application will be reviewed approximately 4 months after the receipt date.



Page Last Updated: February 2011
Content Manager: ClinicalResearchPolicyManager@nhlbi.nih.gov

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