Framingham Heart Study Bibliography

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Years 2000-2004

  1. Fox CS, Cupples LA, Chazaro I, Polak JF, Wolf PA, D'Agostino RB et al. Genomewide linkage analysis for internal carotid artery intimal medial thickness: Evidence for linkage to chromosome 12. American Journal of Human Genetics 2004;74:253-61.

  2. Gorfine M, Hsu L, Prentice RL. Nonparametric correction for covariate measurement error in a stratified Cox model. Biostatistics 2004;5:75-87.

  3. Benjamin EJ, Larson MG, Keyes MJ, Mitchell GF, Vasan RS, Keaney JF et al. Clinical correlates and heritability of flow-medicated dilation in the community-The Framingham Heart Study. Circulation 2004;109:613-19.

  4. Wang TJ, Larson MG, Levy D, Benjamin EJ, Leip EP, Wilson PWF et al. Impact of obesity on plasma natriuretic peptide levels. Circulation 2004;109:594-600.

  5. McKeown NM, Meigs JB, Liu S, Saltzman E, Wilson PWF, Jacques PF. Carbohydrate nutrition, insulin resistance, and the prevalence of the prevalence of the metabolic syndrome in the Framingham Offspring Cohort. Diabetes Care 2004;27:538-46.

  6. Elias MF, Sullivan LM, D'Agostino RB, Elias PK, Beiser A, Au R et al. Framingham stroke risk profile and lowered cognitive performance. Stroke 2004;35:404-09.

  7. Jugdaohsingh R, Tucker KL, Qiao N, Cupples LA, Kiel DP, Powell JJ. Dietary silicon intake is positively associated with bone mineral density in men and premenopausal women of the Framingham Offspring cohort. J Bone Min Res 2004;19:297-307.

  8. Genetic Analysis workshop 13: Analysis of Longitudinal Family Data for Complex Diseases and Related Risk Factors. Almasy, L, Amos, C. I, Bailey-Wilson, J. E, Cantor, R. M, Jaquish, C. E., Martinez, M, Neuman, R. L, Olson, J. M, Palmer, L. J, Rich, S. S, Spence, M. A, and MacCluer, W. J. 4. 12-31-2003.

  9. Miller RR, Zhang Y, Silliman RA, Hayes MK, Leveille SG, Murabito JM et al. Effect of medical contitions on improvement in self-reported and observed functional performance of elders. J Am Geriatr Soc 4 A.D.;52:217-23.

  10. Massaro JM, D'Agostino RB, Sullivan LM, Beiser A, DeCarli C, Au R et al. Managing and analysing data from a large-scale study on Framingham Offspring relating brain structure to cognitive function. Stat Med 2004;23:351-67.

  11. Kannel WB. Hypertension as a risk factor: The Framingham contribution, In: Birkenhager WH, Robertson JIS, Zanchetti A, editors. Handbook of Hypertension, vol. 22.Elsevier B.V.; 2004. p. 129-42.

  12. Kulminski A, Akushevich I, Manton K. Modeling nonlinear effects in longitudinal survival data: Implications for the physiological dynamics of biological systems. Frontiers in Bioscience 2004;9:481-93.

  13. Saccone NL, Goode EL, Bergen AW. Genetic Analysis Workshop 13: Summary of analyses of alcohol and cigarette use phenotypes in the Framingham Heart Study. Genetic Epidemiology 2003;25:S90-S97.

  14. Goldin LR, Camp NJ, Keen KJ, Martin LJ, Moslehi R, Ghosh S et al. Analysis of metabolic syndrome phenotypes in Framingham Heart Study families from Genetic Analysis Workshop 13. Genetic Epidemiology 2003;25:S90-S97.

  15. Bickeboller H, Barrett JH, Jacobs KB, Rosenberger A. Modeling and dissection of longitudinal blood pressure and hypertension phenotypes in genetic epidemiological studies. Genetic Epidemiology 2003;25:S72-S77.

  16. Costello TJ, Falk CT, Ye KQ. Data mining and computationally intensive methods: Summary of group 7 contribution to Genetic Analysis Workshop 13. Genetic Epidemiology 2003;25:S57-S63.

  17. Kraft P, de Andrade M. Group 6: Pleiotropy and multivariate analysis. Genetic Epidemiology 2003;25:S50-S56.

  18. Hauser ER, Hsu FC, Daley D, Olson JM, Rampersaud E, Lin JP et al. Effects of covariates: A summary of Group 5 contributions. Genetic Epidemiology 2003;25:S43-S49.

  19. Badzioch MD, Thomas DC, Jarvik GP. Summary report: Missing data and pedigree and genotyping errors. Genetic Epidemiology 2003;25:S42.

  20. Diego V, Atwood L, Mathias RA, Almasy L. Consistency of genetic analyses in longitudinal data: Observation from the GAW13 Framingham Heart Study data. Genetic Epidemiology 2003;25:S29-S35.

  21. Gauderman WJ, Macgregor S, Briollais L, Scurrah K, Tobin M, Park T et al. Longitudinal data analysis in pedigree studies. Genetic Epidemiology 2003;25:S18-S28.

  22. Strauch K, Golla A, Wilcox MP, Baur MP. Genetic analysis of phenotypes derived from longitudinal data: Presentation Group 1 of genetic analysisi workshop 13. Genetic Epidemiology 2003;25:S5-S17.

  23. Sundstrom J, Sullivan L, D'Agostino RB, Jacques PF, Selhub J, Rosenberg IH et al. Plasma homocysteine, hypertension incidence, and blood pressure tracking - The Framingham Heart Study. Hypertension 2003;42:1100-05.

  24. Russo GT, Friso S, Jacques PF, Rogers G, Cucinotta D, Wilson PWF et al. Age and gender affect the relation between methylenetetrahydrofolate reductase C677T genotype and fasting plasma homocysteine concentration in the Framingham Offspring Study cohort. J Nutr 2003;133:3416-21.

  25. Edmond SL, Felson DT. Function and back symptoms in older adults. J Am Geriatr Soc 2003;51:1702-09.

  26. Wilk JB, DeStefano AL, Joost O, Myers RH, Cupples LA, Slater K et al. Linkage and association with pulmonary function measures on chromosome 6q27 in the Framingham Heart Study. Human Molecular Genetics 2003;12:2745-51.

  27. Mukhopadhyay N, Finegold DN, Larson MG, Cupples LA, Myers RH, Weeks DE. A genome-wide scan for loci affecting normal adult height in the Framingham Heart Study. Human Heredity 2003;55:191-201.

  28. Shearman AM, Cupples LA, Demissie S, Peter I, Schmid CH, Karas RH et al. Association between estrogen receptor alpha gene variation and cardiovascular disease. Jama-Journal of the American Medical Association 2003;290:2263-70.

  29. Levy D, Wilson PWF. Serum insulin-like growth factor I and risk for heart faifure in elderly individuals without a previous myocardial infraction: The Framingham Heart Study. Annals of Internal Medicine 2003;139:642-48.

  30. Roubenoff R, Parise H, Payette HA, Abad LW, D'Agostino R, Jacques PF et al. Cytokines, insulin-like growth factor 1, sarcopenia, and mortality in very old community-dwelling men and women: The Framingham Heart Study. Am J Med 2003;115:429-35.

  31. Cilento BW, Norton SJ, Gates GA. The effects of aging and hearing loss on distortion product otoacoustic emissions. Otolaryng head neck 2003;129:382-89.

  32. Kannel WB, Vasan RS, Levy D. Is the relation of systolic blood pressure to risk of cardiovascular disease continuous and graded, or are there critical values? Hypertension 2003;42:453-56.

  33. Barzilai N, Atzmon G, Schechter C, Schaefer EJ, Cupples AL, Lipton R et al. Unique lipoprotein phenotype and genotype associated with exceptional longevity. Jama-Journal of the American Medical Association 2003;290:2030-40.

  34. Karasik D, Cupples LA, Hannan MT, Kiel DP. Age, gender, and body mass effects on quantitative trait loci for bone mineral density: The Framingham Study. Bone 2003;33:308-16.

  35. Meigs JB, Larson MG, D'Agostino RB, Levy D, Clouse ME, Nathan DM et al. Coronary artery calcification in type 2 diabetes and insulin resistance - The Framingham Offspring Study. Diabetes Care 2002;25:1313-19.

  36. Schaefer EJ, McNamara JR, Shah PK, Nakajima K, Cupples LA, Ordovas JM et al. Elevated remnant-like particle cholesterol and triglyceride levels in diabetic men and women in the Framingham Offspring Study. Diabetes Care 2002;25:989-94.

  37. Meigs JB, D'Agostino RB, Nathan DM, Rifai N, Wilson PWF. Longitudinal association of glycemia and microalbuminuria - The Framingham Offspring Study. Diabetes Care 2002;25:977-83.

  38. Meigs JB, Nathan DM, D'Agostino RB, Wilson PWF. Fasting and postchallenge glycemia and cardiovascular disease risk - The framingham offspring study. Diabetes Care 2002;25:1845-50.

  39. Lloyd-Lones DM, Wilson PWF, Larson MG, Leip E, Beiser A, D'Agostino RB et al. Lifetime risk of coronary heart disease by cholesterol levels at selected ages. Archives of Internal Medicine 2003;163:1966-72.

  40. Murabito JM, Evans JC, Larson MG, Nieto K, Levy D, Wilson PWF. The ankle-brachial index in the elderly and risk of stroke, coronary disease, and death - The Framingham study. Archives of Internal Medicine 2003;163:1939-43.

  41. Payette H, Roubenoff R, Jacques PF, Dinarello CA, Wilson PWF, Abad LW et al. Insulin-Linke growth factor-1 and interleukin 6 predict sarcopenia in very old community-living men and women: The Framingham Heart Study. Journal of the American Geriatrics Society 2003;51:1237-43.

  42. Wang TJ, Evans JC, Benjamin EJ, Levy D, LeRoy EC, Vasan RS. Natural History of Asymptomatic Left Ventricular Systolic Dysfunction in the Community. Circulation 2003;108:977-82.

  43. Natarajan S, Liao YL, Cao GC, Lipsitz SR, McGee DL. Sex differences in risk for coronary heart disease mortality associated with diabetes and established coronary heart disease. Archives of Internal Medicine 2003;163:1735-40.

  44. Meigs JB, Wilson PFW, Nathan DM, D'Agostino RB, Williams K, Haffner SM. Prevalence and characteristics of the metabolic syndrome in the San Antonio Heart and Framingham Offspring Studies. Diabetes 2003;52:2160-67.

  45. Greenland P, Knoll MD, Stamler J, Neaton JD, Dyer AR, Garside DB et al. Major risk factors as antecedent of fatal and nonfatal coronary heart disease events. Jama-Journal of the American Medical Association 2003;290:891-97.

  46. Yang Q, Tofler GH, Cupples LA, Larson MG, Feng DL, Lindpaintner K et al. A genome-wide search for genes affecting circulating fibrinogen levels in the Framingham Heart Study. Thrombosis Research 2003;110:57-64.

  47. Wang TJ, Nam BH, D'Agostino RB, Wolf PA, Lloyd-Jones DM, MacRae CA et al. Carotid Intima-Media Thickness Is Associated With Premature Parental Coronary Heart Disease - The Framingham Heart Study. Circulation 2003;108:572-76.

  48. Bhargava A. A longitudinal analysis of the risk factors for diabetes and coronary heart disease in the Framingham Offspring Study. Population Health Metrics 2003;1.

  49. Marrugat J, D'Agostino R, Sullivan L, Elosua R, Wilson P, Ordovas J et al. An adaptation of the Framingham coronary heart disease risk function to European Mediterranean areas. J Epidemiol Community Health 2003;57:634-38.

  50. Peeters A, Bonneux L, Barendregt JJ, Mackenbach JP. Improvements in Treatment of Coronary Heart Disease and Cessation of Stroke Mortality Rate Decline. Stroke 2003;34:1610-14.

  51. Al Mamun A. Life History of Cardiovascular Disease and Its Risk Factors - Multistate Life Table Approach and Application to the Framingham Heart Study. Amsterdam: Rozenberg Publishers; 2003. p. 1-268.

  52. Wang TJ, Larson MG, Levy D, Vasan RS, Leip EP, Wolf PA et al. Temporal relations of atrial fibrillation and congestive heart failure and their joint influence on mortality- The Framingham Heart Study. Circulation 2003;107:2920-25.

  53. Osgood D, Corella D, Demissie S, Cupples LA, Wilson PWF, Meigs JB et al. Genetic Variation at the scavenger receptor class B type I gene locus deterrmines plasma lipoprotein concentrations and particle size and interacts with type 2 diabetes: The Framingham Study. Journal of Clinical Endocrinology and Metabolism 2003;88:2869-79.

  54. Heo M, Faith MS, Mott JW, Gorman BS, Redden DT, Allison DB. Hierarchical Linear Models for the Development of Growth Curves; An Example with Body Mass Index in Overweight/Obese Adults. Statistics in Medicine 2003;22:1911-42.

  55. Lewington S, Thomsen T, Davidsen M, Sherliker P, Clarke R. Regression Dilution Bias in Blood Total and High-density Lipoprotein Cholesterol and Blood Pressure in the Glostrup and Framingham Prospective Studies. J Cardiovasc Risk 2003;10:143-48.

  56. Panhuysen CIM, Cupples AC, Wilson PWF, Herbert AG, Myers RH, Meigs JB. A Genome Scan for Loci Linked to Quantitative Insulin Traits in Persons Without Diabetes: The Framingham Offspring Study. Diabetologia 3 A.D.;46:579-87.

  57. Karamohamed SDSVJLCC-HNLJSCPCMJWPALCLAHA. Polymorphisms in the Insulin-degrading Enzyme Gene are Associated with type 2 Diabetes in Men from the NHLBI Framingham Heart Study. Diabetes 3 A.D.;52:1562-67.

  58. Kleijn M, et tal. Intake of Dietary Phytoestogens is Low in Postmenopausal Women in the United States: The Framingham Study. Am J Epidemiol 2002;2002:1021-27.

  59. Vasan RS, Larson MG, Levy D, Galderisi M, Wolf PA, Benjamin EJ. Doppler transmitral flow indexes and risk of atrial fibrillation (The Framingham Heart Study). Am J Cardiol 2003;91:1079-83.

  60. Tan ZS, Seshadri S, Beiser A, Wilson PWF, Kiel DP, Tocco MD et al. Plasma total cholesterol level as a risk factor for Alzheimer disease - The Framingham study. Arch Intern Med 2003;163:1053.

  61. Djousse, L., Rothman, K. J., Cupples, L. A., Levy, D., and Ellison, R. C. Effect of serum albumin and bilirubin on the risk of myocardial infarction (the Framingham Offspring Study). Amer J Cardiol 91(4), 485-490. 2-15-2003.

  62. Fox, C. S., Vasan, R. S., Parise, H., Levy, D., O'Donnell, C. J., D'Agostino, R. B., and Benjamin, E. J. Mitral annular calcification predicts cardiovascular morbidity and mortality - The Framingham Heart Study. Circulation 107(11), 1492-1496. 3-25-2003.

  63. Benjamin, E. J., Sawyer, D. B., Levy, D., Wilson, P. W. F., and D'Agostino, R. B. Inflammatory markers and risk of heart failure in elderly subjects without prior myocardial infarction. Circulation 107(11), 1486-1491. 3-25-2003.

  64. Hadigan, C., Meigs, J. B., Wilson, P. W. F., D'Agostino, R. B., Davis, B., Basgoz, N., Sax, P. E., and Grinspoon, s. Prediction of coronary heart disease risk in HIV-infected patients with fat redistribution. Clin Infectious Dis 36(7), 909-916. 4-1-2003.

  65. Walter, R. E., Beiser, A., Givelber, R. J., O'Conner, G. T., and Gottlieb, D. J. Association between glycemic state and lung function- - The Framingham Heart Study. 167(6), 911-916. 3-15-2003.

  66. Niu, J., Zhang, Y., LaValley, M., Chaisson, C. E, Aliabadi, P., and Felson, D. T. Symmetry and clustering of symptomatic hand osteoarthritis in elderly men and women: the Framingham Study. Rheumatology 42(2), 343-348. 2-1-2003.

  67. DeStefano, A. L., Gates, G. A., Heard-Costa, N., Myers, R. H., and Baldwin, C. T. Genomewide linkage analysis to presbycusis in the Framingham Heart Study. Arch Otolar-Head Neck Surgery 129(3), 285-289. 3-1-2003.

  68. Keaney, J. F., Larson, M. G., Vasan, R. S., Wilson, P. W. F., Lipinska, I, Corey, D., Massaro, J. M., Sutherland, P., Vita, J. A., and Benjamin, E. J. Obesity and systematic oxidative stress - clinical correlates of oxidative stress in the Framingham Study. Arterioscler Thromb Vasc Biol 129(3), 434-439289. 3-1-2003.

  69. Vasan, R. S., Beiser, A., D'Agostino, R. B., Levy, D., Selhub, J., Jacques, P. F., Rosenberg, I. H., and Wilson, P. W. F. Plasma homocysteine and risk for congestive heart failure in adults without prior myocardial infarction. JAMA 289(10), 1251-1257. 3-12-2003.

  70. Hiller, R., Sperduto, R. D., Reed, G. F., D'Agostino, R. B., and Wilson, P. W. F. Serum lipids and age-related lens opacities: A longitudinal investigation. Ophthalmol 110(3), 578-583. 3-1-2003.

  71. Zhang, Y. Q., Kiel, D. P., Ellison, R. C., Schatzkin, A., Dorgan, J. F., Kreger, B. E., Cupples, L. A., and Felson, D. T. Bone mass and the risk of prostate cancer: The Framingham Study. Amer J Med 113(9), 734-739. 12-15-2002.

  72. Singh, J. P., Larson, M. G., O'Donnell, C. J., Tsuji, H., Corey, D., and Levy, D. Genome scan linkage results for heart rate variability (The Framingham Heart Study). Am J Cardiol 90(12), 1290-1293. 12-15-2002.

  73. Lloyd-Jones, D. M., Larson, M. G., Leip, E. P., Beiser, A., D'Agostino, R. B., Kannel, W. B., Murabito, J. M., Vasan, R. S., Benjamin, E. J., and Levy, D. Lifetime risk for developing congestive heart failure- The Framingham Heart Study. Circulation 106(24), 3068-3072. 12-10-2002.

  74. Djousse, L., Rothman, K. J., Cupples, L. A., Levy, D., and Ellison, R. C. Serum albumin and risk of myocardial infarction and all-cause mortality in the Framingham Offspring. Circulation 106(23), 2919-2924. 12-3-2002.

  75. Djousse, L., Dorgan, J. F., Zhang, Y. Q., Schatzkin, A., Hood, M., D'Agostino, R. B., Copenhafer, D. L., Kreger, B. E., and Ellison, R. C. Alcohol consumptin and risk of lung cancer: The Framingham study. J.Natl.Cancer Inst. 94(24), 1877-1882. 12-18-2002.

  76. Millen, B. E., Quatromoni, P. A., Nam, B. H., O'Horo, C. E., Polak, J. F., and D'Agostino, R. B. Dietary patterns and the odds of carotid atherosclerosis in women: The Framingham nutrition studies. Prev.Med. 35(6), 540-547. 12-1-2002.

  77. Zhang, Y. Q., Norman, J. E., Kelly-Hayes, M., Chaisson, C. E., Aliabadi, P., and Felson, D. T. Prevalence of symptomatic hand osteoarthritis and its impact on functional status among the elderly - The Framingham Study. Amer J Epidemiol 156(11), 1021-1027. 12-1-2002.

  78. Fleming, D. J., Tucker, K. L., Jacques, P. F., Dallal, G. E., Wilson, P. W. F., and Wood, R. J. Dietary factors associated with the risk of high iron stores in the elderly Framingham Heart Study cohort. Amer J Clin Nutr 76(6), 1375-1384. 12-1-2002.

  79. Karasik, D., Rosen, C. J., Hannan, M. T., Broe, K. E., Dawson-Hughes, B., Gagnon, D. R., Wilson, P. W. F., Visser, M., Langlois, J. A., Mohan, S., and Kiel, D. P. Insulin-like growth factor binding proteins 4 and 5 and bone mineral density in elderly men and women. Calcified Tissue Intl 71(4), 323-328. 10-1-2002.

  80. Lloyd-Jones, D. M., Evans, J. C., Larson, M. G., and Levy, D. Treatment and control of hypertension in the community- a prospective analysis. Hypertension 40(5), 640-646. 11-1-2002.

  81. Djousse, L., Knowlton, B., Cupples, L. A., Marder, K., Shoulson, I., and Myers, R. H. Weight loss in early stage of Huntington's disease. Neurology 59(9), 1325-1330. 11-12-2002.

  82. Tofler, G. H., D'Agostino, R. B., Jacques, P. F., Bostom, A. G., Wilson, P. W. F., Lipinska, I., Mittleman, M. A., and Selhub, J. Association between increased homocysteine levels and impaired fibrinolytic potential: potential mechanism for cardiovascular risk. Thrombosis and Haemostasis 88(5), 799-804. 11-1-2002.

  83. Atwood, L. D., Heard-Costa, N. L., Cupples, L. A., Jaquish, C. E., Wilson, P. W. F., and D'Agostino, R. B. Genomewide linkage analysis of body mass index across 28 years of the Framingham Heart Study. Amer J Human Gen 71(5), 1044-1050. 11-1-2002.

  84. Ordovas, J. M., Corella, D., Demissie, S., Cupples, L. A., Couture, P., Coltell, O., Wilson, P. W. F., Schaefer, E. J., and Tucker, K. L. Dietary fat intake determines the effect of a common polymorphism in the hepatic lipase gene promoter on high-density lipoprotein metabolism- evidence of a strong dose effect in this gene-nutrient interaction in the Framingham Study. Circulation 106(18), 2315-2321. 10-29-2002.

  85. Greenberg, J. A. Hypothesis- The J-shaped follow-up relation bewtween mortality risk and disease risk-factor is due to statistical confounding. medical hypotheses 59(5), 568-576. 11-1-2002.

  86. Karasik, D., Myers, R. H., Hannan, M. T., Gagnon, D., McLean, R. R., Cupples, L. A., and Kiel, D. P. Mapping of quantitative ultrasound of the calcaneus bone to chromosome 1 by genome-wide linkage analysis. Osteoporosis Intl 13(10), 796-802. 8-1-2002.

  87. Wang, T. J., Nam, B. H., Wilson, P. W. F., Wolf, P. A., Levy, D., Polak, J. F., D'Agostino, R. B., and O'Donnell, C. J. Association of C-reactive protein with carotid atherosclerosis in men and women: The Framingham Heart Study. Arterioscler Thromb Vasc Biol 22(10), 1662-1667. 10-1-2002.

  88. Levy, D., Kenchaiah, S., Larson, M. G., Benjamin, E. J., Kupka, M. J., Ho, K. K. L., Murabito, J. M., and Vasan, R. S. Long term trends in the incidence of and survival with heart failure. N Engl J Med 347(18), 1397-1402. 10-31-2002.

  89. Haider, A. W., Wilson, P. W. F., Larson, M. G., Evans, J. C., Michelson, E. L., Wolf, P. A., O'Donnell, C. J., and Levy, D. The association of seropositivity to helicobacter pylori, chlamydia pneumonia, and cytomegalovirus with risk of cardiovascular disease- a prospective study. J Am Coll Cardiol 40(8), 1408-1413. 10-16-2002.

  90. Morshedi-Meibodi, A., Larson, M. G., Levy, D., O'Donnell, C. J., and Vasan, R. S. Heart rate recovery after treadmill exercise testing and risk of cardiovascular disease events (The Framingham Heart Study). Amer J Cardiol 90(8), 848-852. 10-15-2002.

  91. Kannel, W. B., Wilson, P. W. F., Nam, B. H., and D'Agostino, R. B. Risk stratification of obesity as a coronary risk factor. Amer J Cardiol 90(7), 697-701. 10-1-2002.

  92. Walsh, C. R., Cupples, L. A., Levy, D., Kiel, D. P., Hannan, M., Wilson, P. W. F., and O'Donnell, C. J. Abdominal aortic calcific deposits are associated with increased risk for congestive heart failure: The Framingham Heart Study. Amer Heart J 144(4), 733-739. 10-1-2002.

  93. Freed, L. A., Benjamin, E. J., Levy, D., Larson, M. G., Evans, J. C., Fuller, D. L., Lehman, B., and Levine, R. A. MItral valve prolapse in the general population - the benign nature of echocardiographic features in the Framingham Heart Study. J Am Coll Cardiol 40(7), 1298-1304. 10-22-2002.

  94. Fine-Edelstein, JS, Wolf, P. A., O'Leary, D. H., Poehlman, M. S., Belanger, A. J., Kase, C. S., and D'Agostino, R. B. Precursors of extracranial carotid atherosclerosis in the Framingham study. Neurology 44, 1046-1050. 6-1-1994.

  95. Wang, T. J., Larson, M. G., Levy, D., Benjamin, E. J., Kupka, M. J., Manning, W. J., Clouse, M. E., D'Agostino, R. B., Wilson, P. W. F., and O'Donnell, C. J. C-reactive protein is associated with subclinical epicardial coronary calcification in men and women - the Framingham Heart Study. Circulation 106(10), 1189-1191. 9-3-2002.

  96. Choumenkovitch, S. F., Selhub, J., Wilson, P. W. F., Rader, J. I., Rosenberg, I. H., and Jacques, P. F. Folic acid intake from fortification in United States exceeds prediction. J Nutr 132(9), 2792-2798. 9-1-2002.

  97. Wilson, P. W. F., D'Agostino, R. B., Sullivan, L., Parise, H., and Kannel, W. B. Overweight and obesity as determinants of cardiovascular risk - the Framingham experience. Arch Intern Med 162(16), 1867-1872. 9-9-2002.

  98. Quatromoni, P. A., Copenhafer, D. L., D'Agostino, R. B., and Millen, B. E. Dietary patterns predict the development of overweight in women: The Framingham Nutrition Studies. J Am Diet Assoc 102(9), 1240-1246. 9-1-2002.

  99. Evans, J. C., Larson, M. G., Chen, M. H., Chen, L., Benjamin, E. J., and Levy, D. Incidence and prognosis of syncope. N Engl J Med 347(12), 878-885. 9-19-2002.

  100. Vasan, R. S., Benjamin, E. J., Larson, M. G., Leip, E. P., Wang, T. J., Wilson, P. W. F., and Levy, D. Plasma Natriuretic peptides for community screening for left ventricular hypertrophy and systolic dysfunction- The Framingham Heart Study. JAMA 288(10), 222-228. 9-11-2002.

  101. Karasik, D., Myers, R. H., Cupples, L. A., Hannan, M. T., Gagnon, D. R., Herbert, A., and Kiel, D. P. Genome screen for quantitative trait loci contributing to normal variation in bone mineral density: The Framingham Study. Journal Bone and Min Res 17(9), 1718-1727. 9-2-2002.

  102. Jugdaohsingh, R., McGee, D., Davidsen, M., and Jorgensen, T. A cross-validation of risk-scores for coronary heart disease mortality based on data from the Glostrup population studies and Framingham Heart Study. Int.J.Epidemiol. 31(4), 817-822. 8-2-2002.

  103. McKeown, N. M., Meigs, J. B., Liu, S. M., Wilson, P. W. F., and Jacques, P. F. Whole grain intake is favorably associated with metabolic risk factors for type 2 diabetes and cardiovascular disease in the Framingham Offspring Study. Am J Clin Nutr 76(2), 390-398. 8-2-2002.

  104. Brousseau, M. E., O'Connor, J. J., Ordovas, J. M., Collins, D., Otvos, J. D., Massov, T., McNamara, J. R., Rubins, H. B., Robins, S. J., and Schaefer, E. J. Cholesterol ester transfer protein Taqi B2B2 genotype is associated with higher HDL cholesterol levels and lower risk of coronary heart disease end points in men with HDL deficiency - Veterans Affairs HDL cholesterol intervention trial. Arterioscler Thromb Vasc Biol 22(7), 1148-1154. 7-1-2002.

  105. O'Donnell, C. J., Chazaro, I., Wilson, P. W. F., Fox, C., Hannan, M. T., Kiel, D. P., and Cupples, L. A. Evidence for heritability of abdominal calcific deposits in the Framingham Heart Study. Circulation 106(3), 337-341. 7-16-2002.

  106. Kenchaiah, S., Evans, J. C., Levy, D., Wilson, P. W. F., Benjamin, E. J., Larson, M. G., Kannel, W. B., and Vasan, R. S. Obesity and the Risk of Heart Failure. N Engl J Med 347(5), 305-313. 8-1-2002.

  107. Murabito, J. M., Evans, J. C., Nieto, K., Larson, M. G., Levy, D., and Wilson, P. W. F. Prevalence and clinical correlates of peripheral arterial disease in the Framingham Offspring. Amer Heart J 143(6), 961-965. 6-1-2002.

  108. Tucker, K. L., Chen, H. L., Hannan, M. T., Cupples, L. A., Wilson, P. W. F., Felson, D., and Kiel, D. P. Bone mineral density and dietary patterns in older adults: the Framingham osteoporosis study. Amer J Clin Nutr 76(1), 245-252. 7-1-2002.

  109. Kerr, W. C., Fillmore, K. M., and Bostrom, A. Stability of alcohol consumption over time: evidence from three longitudinal surveys from the United States. J Stud Alcohol 63(3), 325-333. 5-1-2002.

  110. Glickman, M. E. and Gagnon, D. R. Modeling the effects of genetic factors on late-onset diseases in cohort studies. Lifetime Data Analysis 8(3), 211-228. 9-1-2002.

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  112. Vargas-Martinez, C., Ordovas, J. M., Wilson, P. W., and Selhub, J. The glutamate carboxypeptidase gene II (C>T) polymorphism does not affect folate status in the Framingham Offspring cohort. J Nutr 132(6), 1176-1179. 6-1-2002.

  113. Freed, L. A., Levy, D., Levine, R. A., Evans, J. C., Larson, M. G., Fuller, D. L., Lehman, B., and Benjamin, E. J. Mitral valve prolapse and atrial septal aneurysm: an evaluation in the Framingham Heart Study. Am.J.Cardiol. 89(11), 1326-1330. 6-1-2002.

  114. Felson, D. T., Nevitt, M. C., Zhang, Y. Q., Aliabadi, P., Baumer, B., Gale, D., Li, W., Yu, W., and Xu, L. High prevalence of lateral knee osteoarthritis in Beijing Chinese compared with Framingham caucasian subjects. Arthritis Rheum 46(5), 1217-1222. 5-1-2002.

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  116. Jaffer, F. A., O'Donnell, C. J., Larson, M. G., Chan, S. K., Kissinger, K. V., Kupka, M. J., Salton, C., Botnar, R. M., Levy, D., and Manning, W. J. Age and sex distribution of subclinical aortic atherosclerosis - a magnetic resonance imaging examination of the Framingham Heart Study. Arterioscler Thromb Vasc Biol 22(5), 849-854. 5-1-2002.

  117. Tai, E. S., Demissie, S., Cupples, L. A., Corella, D., Wilson, P. W., Schaefer, E. J., and Ordovas, J. M. Association between the PPARA L162V polymorphism and plasma lipid levels - the Framingham offspring study. Arterioscler Thromb Vasc Biol 22(5), 805-810. 5-1-2002.

  118. Samelson, E. J., Zhang, Y. Q., Kiel, D. P., Hannan, M. T., and Felson, D. T. Effect of birth control on risk of hip fracture: age specific incidence rates in the Framingham Study. Am J Public Health 92(5), 858-862. 5-1-0002.

  119. Jugdaohsingh, R., Anderson, S. H. C., Tucker, K. L., Elliot, H., Kiel, D. P., Thompson, R. P. H., and Powell, J. J. Dietary silicon intake and absorption. Amer J Clin Nutr 75(5), 887-893. 2002.

  120. Quatromoni, P. A., Copenhafer, D. L., Demissie, S., D'Agostino, R. B., O'Horo, C. E., Nam, B. H., and Millen, B. E. The internal validity of a dietary pattern analysis: the Framingham nutrition studies. J.Epi and Comm Health 5(56), 381-388. 5-1-2002.

  121. Demissie, S., Cupples, L. A., Myers, R., Aliabadi, P., Levy, D., and Felson, D. T. Genome scan for quantity of hand osteoarthritis - the Framingham study. Arthritis Rheum 4(46), 946-952. 4-1-0002.

  122. Djousse, L., Ellison, R. C., Beiser, A., Scaramucci, A., D'Agostino, R. B., and Wolf, P. A. Alcohol consumption and risk of ischemic stroke - the Framingham study. Stroke 33(4), 907-912. 4-1-2002.

  123. Salton, C. J., Chuang, M. L., O'Donnell, C. J., Kupka, M. J., Larson, M. G., Kissinger, K. V., Edelman, R. R., Levy, D., and Manning, W. J. Gender differences and normal left ventricular anatomy in an adult population free of hypertension - a cardiovascular magnetic resonance study of the Framingham Heart Study offspring cohort. J Am Coll Cardiol 39(6), 1055-1060. 3-20-2002.

  124. Joost, O., Wilk, J. B., Cupples, L. A., Harmon, M., Shearman, A. M., Baldwin, C. T., O'Conner, G. T., Myers, R. H., and Gottlieb, D. J. Genetic loci influencing lung function - a genomewide scan in the Framingham study. Am J Respir Crit Care Med 165(6), 795-799. 3-15-2002.

  125. Peeters, A., Mamun, A. A., Willekens, F., and Bonneux, L. A cardiovascular life history - a life course analysis of the original Framingham Heart Study cohort. Eur Heart J 23(6), 458-466. 3-1-2002.

  126. Cornfield, J. and Mitchell, S. Selected risk factors in coronary disease. arch environ health 19(1), 382-394. 9-1-1969.

  127. Gates, G. A., Beiser, A., Rees, T. S., D'Agostino, R. B., and Wolf, P. A. Central auditory dysfunction may precede the onset of clinical demetia in people with probable Alzheimer's disease. J Amer Geriatrics 50(3), 482-488. 3-1-2002.

  128. Meigs, J. B., Panhuysen, C. I. M., Myers, R. H., Wilson, P. W. F., and Cupples, L. A. A genome-wide scan for loci linked to plasma levels of glucose and HbA(1c) in a community-based sample of caucasion pedigrees- the Framingham Offspring Study. Diabetes 51(3), 833-840. 3-1-2002.

  129. Rodriguez, B. L., D'Agostino, R., Abbott, R. D., Kagan, A., Burchfiel, C. M., Yano, K., Ross, G. W., Silbershatz, H., Higgins, M. W., Popper, J., Wolf, P. A., and Curb, J. D. Risk of hospitalized stroke in men enrolled in the Honolulu Heart Program and the Framingham Study- a comaprison of incidence and risk factor effects. Stroke 33(1), 230-236. 1-1-2002.

  130. Vasan, R. S., Beiser, A., Seshadri, S., Larson, M. G., Kannel, W. B., D'Agostino, R. B., and Levy, D. Residual lifetime risk for developing hypertension in middle-aged women and men- the Framingham Heart Study. JAMA 287(8), 1003-1010. 2-27-2002.

  131. Walsh, C. R., Larson, M. G., Vasan, R. S., and Levy, D. Serum potassium is not associated with blood pressure tracking in the Framingham Heart Study. Am.J.Hypertens. 15(2), 130-136. 2-1-2002.

  132. Seshadri, S., Beiser, A., Selhub, J., Jacques, P. F., Rosenberg, I. H., D'Agostino, R. B., Wilson, P. W. F., and Wolf, P. A. Plasma Homocysteine as a risk factor for dementia and Alzheimer's disease. N Engl J Med 346(7), 476-483. 2-14-2002.

  133. Jacques, P. F., Kalmbach, R., Bagley, P. J., Russo, G. T., Rogers, G., Wilson, P. W. F., Rosenberg, I. H., and Selhub, J. The relationshsip between riboflavin and plasma total homocystein in the framingham offspring cohort is influenced by floate status and the C677T transition in the methylenetetrahydrofolate reductase gene. J Nutr 132(2), 283-288. 2-1-2002.

  134. de Kleijn M.J.J., van der Schouw Y.T., Wilson, P. W. F., Grobbee, D. E., and Jacques, P. F. Dietary intake of Phytoestrogens is associated with a favorable metabolic cardiovascular risk profile in postmenopausal US women: the Framingham Study. J Nutr 132(2), 276-282. 2-1-2002.

  135. Walsh, C. R., Larson, M. G., Evans, J. C., Djousse, L., Ellison, R. C., Vasan, R. S., and Levy, D. Alcohol consumption and risk for conjestive heart failure in the framingham heart study. Annals of Internal Medicine 136(3), 181-191. 2-5-2002.

  136. Tucker, K. L., Hannan, M. T., and Kiel, D. P. The acid-base hypothesis: diet and bone in the Framingham Osteoporosis Study. European J of Nutrition 40(5), 231-237. 10-7-2001.

  137. Baldwin, C. T., Cupples, L. A., Joost, O., Demissie, S., Chaisson, C., McAlindon, T., Myers, R. H., and Felson, D. Absence of linkage or association for osteoarthritis with the vitamin D receptor/type II collagen locus: The Framingham Osteoarthritis Study. J.Rheumatol 29(1), 161-165. 1-1-2002.

  138. Vasan, R. S., Massaro, J. M., Wilson, P. W. F., Seshadri, S, Wolf, P. A., Levy, D., and D'Agostino, R. B. Antecedent blood pressure and risk of cardiovascular disease- The Framingham Heart Study. Circulation 105(1), 48-53. 1-1-2002.

  139. Wilson, S. L. and Poulter, N. R. Cardiovascular risk: its assessment in clinical practice. Brit J Biomed Sci 58(4), 248-251. 12-1-2001.

  140. Galluzzi, J. R., Cupples, L. A., Otvos, J. D., Wilson, P. W. F., Schaefer, E. J., and Ordovas, J. M. Association of the A/T54 polymorphism in the intestinal fatty acid binding protein with variations in plasma lipids in the Framingham Offspring Study. 12-8-2001.

  141. Ordovas, J. M., Corella, D., Cupples, L. A., Demissie, S., Kelleher, A., Coltell, O., Wilson, P. W. F., Schaefer, E. J., and Tucker, K. Polyunsaturated fatty acids modulate the effects of the APOA1 G-A polymorphism on HDL-cholesterol concentrations in a sex-specific manner: the Framingham Study. Am J Clin Nutr 75(1), 38-46. 1-9-2002.

  142. Choumenkovitch, S. F., Jacques, P. F., Nadeau, M. R., Wilson, P. W. F., Rosenberg, I. H., and Selhub, J. Folic acid fortification increases red blood cell folate concentrations in the Framingham Study. J Nutr 131(12), 3277-3280. 12-4-2001.

  143. Zhang, Y. Q., Xu, L., Nevitt, M. C., Aliabadi, P., Yu, W., Qin, M. W., Lui, L. Y., and Felson, D. T. Comparison of the prevalance of knee osteoarthritis between the elderly Chinese population in Beijing and whites in the United States - The Beijing osteoarthritis study. Arthritis Rheum 44(9), 2065-2071. 9-7-2001.

  144. Gottlieb, D. J., Wilk, J. B., Harmon, M., Evans, J. C., Joost, O., Levy, D., O'Conner, G. T., and Myers, R. H. Heritability of longitudinal change in lung function - the Framingham Study. Am J Respir Crit Care Med 164(9), 1655-1659. 11-1-2001.

  145. Vasan, R. S., Larson, M. G., Leip, E. P., Kannel, W. B., and Levy, D. Assessment of frequency of progression to hypertension in nonhypertensive participants in the Framingham Heart Study: a cohort study. Lancet 358(9294), 1682-1686. 11-17-2001.

  146. Kiel, D. P., Hannan, M. T., Broe, K. E., Felson, D. T., and Cupples, L. A. Can metacarpal cortical area predict the occurence of hip fracture in women and men over 3 decades of follow-up? Results from the Framingham Osteoporosis Study. J Bone Min Res 16(12), 2260-2266. 12-1-2001.

  147. Rost, N. S., Wolf, P. A., Kase, C. S., Kelly-Hayes, M., Silbershatz, H., Massaro, J. M., D'Agostino, R. B., Franzblau, C., and Wilson, P. W. F. Plasma concentration of C-reactive protein and risk of ischemic stroke and transient ischmiec attack - the Framingham study. Stroke 32, 2575-2579. 11-5-2001.

  148. Murabito, J. M., Evans, J. C., Larson, M. G., Kreger, B. E., Splansky, G. L., Freund, K. M., Moskowitz, M. A., and Wilson, P. W. F. Family breast cancer history and mammography - Framingham offspring study. Amer J Epidemiol 154, 916-923. 11-15-2001.

  149. Vasan, R. S., Larson, M. G., Leip, E. P., Evans, J. C., O'Donnell, C. J., Kannel, W. B., and Levy, D. Impact of high-normal blood pressure on the risk of cardiovascular disease. N Engl J Med 345, 1291-1297. 11-1-2001.

  150. LaValley, M., McAlindon, T. E., Evans, S., Chaisson, C. E., and Felson, D. T. Problems in the development and validatioin of questionnaire based screen instruments for ascertaining cases with sympotomatic knee osteoarthritis - The Framingham Study. Arthritis Rheum 44, 1105-1113. 5-1-2001.

  151. Seshadri, S, Wolf, P. A., Beiser, A., Vasan, R. S., Wilson, P. W. F., Kase, C. S., Kelly-Hayes , M., Kannel, W. B., and D'Agostino, R. B. Elevated midlife blood pressure increases stroke risk in elderly person- the Framingham study. Arch Intern Med 161, 2343-2350. 10-22-2001.

  152. Haveman-Nies, A, Tucker, K. L., de Groot LCPGM, Wilson, P. W. F., and van Staveren, W. A. Evaluation of dietary quality in relationship to nutritional and lifestyle factors in elderly people in the US Framingham Heart Study and the European SENECA study. European J of Clin Nutr 55, 870-880. 10-1-2001.

  153. Guidry, U. C., Mendes, L. A., Evans, J. C., Levy, D., O'Conner, G. T., Larson, M. G., Gottlieb, D. J., and Benjamin, E. J. Echocardiographic features of the right heart in sleep disordered breathing - the Framingham Heart Study. Am J Respir Crit Care Med 164, 933-938. 9-15-2001.

  154. Meigs JB, Haffner SM, Nathan DM, D'Agostino RB, Wilson PWF. Sample exchange to compare insulin measurements between the San Antonio Heart Study and the Framingham Offspring Study. J Clin Epidemiol 2001;54:1031-36.

  155. Mukamal KJ, Jadhav PP, D'Agostino RB, Massaro JM, Mittleman MA, Lipinska I et al. Alcohol consumption and hemostatic factors: analysis of the Framingham offspring cohort. Circulation 2001;104:13.

  156. Millen BE, Quatromoni PA, Copenhafer DL, Demissie S, O'Horo CE, D'Agostino RB. Validation of a dietary pattern approach for evaluating nutritional risk: The Framingham Nutrition Studies. J Am Diet Assoc 2001;101:187-94.

  157. Russo GT, Meigs JB, Cupples LA, Demissie S, Otvos JD, Wilson PWF et al. Association of the Sst-1 polymorphism at the APOC3 gene locus with variations in lipid levels, lipoprotein subclass profiles and coronary heart disease risk: the Framingham offspring study. Atherosclerosis 2001;158:173-81.

  158. Fleming DJ, Jacques PF, Massaro JM, D'Agostino RB, Wilson PWF, Wood RJ. Aspirin intake and the use of serum ferritin as a measure of iron status. Am.J.Clin.Nutr. 2001;74:219-26.

  159. Meigs JB, Jacques PF, Selhub J, Singer DE, Nathan DM, Rifai N et al. Fasting plasma homocysteine levels in the insulin resistance syndrome - The Framingham Offspring Study. Diabetes Care 2001;24:1403-10.

  160. Feng DL, Lindpaintner K, Larson MG, O'Donnell CJ, Lipinska I, Sutherland PA et al. Platelet glycoprotein IIIa P1(A) polymorphism, fibrinogen, and platelet aggregability - The Framingham Heart Study. Circulation 2001;104:140-44.

  161. D'Agostino RB, Grundy S, Sullivan LM, Wilson P. Validation of the Framingham Coronary Heart Disease prediction scores - results of a multiple ethnic groups investigation. JAMA 2001;286:180-87.

  162. O'Donnell CJ, Larson MG, Feng DL, Sutherland PA, Lindpaintner K, Myers RH et al. Genetic and environmental contribution to platelet aggregation - The Framingham Heart Study. Circulation 2001;103:3051-56.

  163. Wilson PWF, Kauppila LI, O'Donnell CJ, Douglas PK, Hannan M, Polak J et al. Abdominal aortic calcific deposits are an important predictor of vascular morbidity and mortality. Circulation 2001;103:1529-34.

  164. Adlercreutz H, Mazur W, Grobbee DE, Jacques PF. Intake of dietary phytoestrogens is low in postmenopausal women in the United States: The Framingham Study. J Nutr 2001;131:1826-32.

  165. Galluzzi JR, Cupples LA, Meigs JB, Wilson PFW, Schaefer EJ, Ordovas JM. Association of the ala54-thr polymorphism in the intestinal fatty acid-binding protein with 2-h postchallenge insulin levels in the Framingham Offspring Study. Diabetes Care 2001;24:1161-66.

  166. Worzala K, Hiller R, Sperduto RD, Mutalik K, Murabito JM, Moskowitz M et al. Postmenopausal estrogen use, type of menopause, and lens opacities- The Framingham Studies. Arch.Intern.Med. 2001;161:1448-54.

  167. Friso S, Jacques PF, Wilson PWF, Rosenberg IH, Selhub J. Low circulating vitamin B-6 is associated with elevation of the inflammation marker C-reactive protein independently of plasma homocysteine levels. Circulation 2001;103:2788-91.

  168. Kiel DP, Kauppila LI, Cupples LA, Hannan MT, O'Donnell CJ, Wilson PWF. Bone loss and the progression of abdominal aortic calcification over a 25 year period: The Framingham Heart Study. Calcified Tissue Intl 2001;68:271-76.

  169. Franklin SS, Larson MC, Khan SA, Wong ND, Leip EP, Kannel WB et al. Does the relation of blood pressure to coronary heart disease risk change with aging? The Framingham Heart Study. Circulation 2001;103:1245-49.

  170. Djousse L, Levy D, Cupples LA, Evans JC, D'Agostino RB, Ellison RC. Total serum bilirubin and risk of cardiovascular disease in the Framingham Offspring Study. Amer J Cardiol 2001;87:1196-200.

  171. Lloyd-Jones DM, O'Donnell CJ, D'Agostino RB, Massaro J, Silbershatz H, Wilson PWF. Applicability of cholesterol-lowering primary prevention trials to a general population - The Framingham heart study. Arch.Intern.Med. 2001;161:949-54.

  172. Corella D, Tucker K, Lahoz C, Coltell O, Cupples LA, Wilson PEF et al. Alcohol drinking determines the effect of the APOE locus on LDL-cholesterol concentrations in men: the Framingham Offspring Study. Am J Clin Nutr 2001;73:736-45.

  173. Zee RYL, Myers RH, Hannan MT, Wilson PWF, Ordovas JM, Schaefer EJ et al. Absence of linkage for bone mineral density to chromosome 12q12-14 in the region of the vitamin D receptor gene. Calcified Tissue Intl 2001;67:434-39.

  174. Brousseau ME, Bodzioch M, Schaefer EJ, Goldkamp AL, Kielar D, Probst M et al. Common varients in the gene encoding ATP-binding cassette transporter 1 in men with low HDL cholesterol levels and coronary heart disease. Atherosclerosis 2001;154:607-11.

  175. Lahoz C, Schaefer EJ, Cupples LA, Wilson PWF, Levy D, Osgood D et al. Apolipoprotein E genotype and cadiovascular disease in the Framingham Heart Study. Atherosclerosis 2001;154:529-37.

  176. Fleming DJ, Jacques PF, Tucker KL, Massaro JM, D'Agostino RB, Wilson PWF et al. Iron status of the free-living, elderly Framingham Heart Study cohort: an iron-replete population with high prevalence of elevated iron stores. Am J Clin Nutr 2001;73:638-46.

  177. Jacques PF, Bostom AG, Wilson PWF, Rich S, Rosenberg IH, Selhub J. Determinants of plasma total homocysteine concentration in the Framingham Offspring cohort. Am J Clin Nutr 2001;73:613-21.

  178. Hadigan C, Meigs JB, Rabe J, D'Agostino RB, Wilson PWF, Lipinska I et al. Increased PAI-1 and tPA antigen levels are reduced with metformin therapy in HIV-infected patients with fat redistribution and insulin resistance. J.Clin.Endocrinol.Metab. 2001;86:939-43.

  179. LaValley MP, McAlindon TE, Chaisson CE, Levy D, Felson DT. The validity of different definitions of radiographic worsening for longitudinal studies of knee osteoarthritis. J.Clin.Epidemiol. 2001;54:30-39.

  180. Feng DL, D'Agostino RB, Silbershatz H, Lipinska I, Massaro J, Levy D et al. Hemostatic state and atrial fibrillation (The Framingham Offspring study). Am J Cardiol 2001;87:168-71.

  181. Zhang YQ, Felson DT, Ellison RC, Kreger BE, Schatzkin A, Dorgan JF et al. Bone mass and the risk of colon cancer among postmenopausal woman- The Framingham Study. Am J Epidemiol 2001;153:31-37.

  182. McNamara JR, Shah PK, Nakajima K, Cupples LA, Wilson PWF, Ordovas JM et al. Remnant-like particle (RLP) cholesterol is an independent cardiovascular disease risk factor in women: results from the Framingham Heart Study. Atherosclerosis 2001;154:229-36.

  183. Djousse L, Levy D, Murabito JM, Cupples LA, Ellison RC. Alcohol consumption and risk of intermittent claudication in the Framingham Heart Study. Circulation 2000;102:3092-97.

  184. Amin S, Zhang YQ, Sawin DT, Evans SR, Hannan MT, Kiel DP et al. Association of hypogonadism and estradiol levels with bone mineral density in elderly men for the Framingham study. Ann Intern Med 2000;133:951-63.

  185. Meigs JB, Cupples LA, Wilson PWF. Parental transmission of type 2 diabetes. Diabetes 2000;49:2201-07.

  186. Levy D, DeStefano AL, Larson MG, O'Donnell CJ, Lifton RP, Gavras H et al. Evidence for a gene influencing blood pressure on chromosome 17: genome scan linkage results for longitudinal blood pressure phenotypes in subjects from the Framingham Heart Study. Hypertension 2000;36:477-83.

  187. Stec JJ, Silbershatz H, Tofler GH, Matheney TH, Sutherland P, Lipinska I et al. Association of fibrinogen with cardiovascular risk factors and cardiovascular disease in the Framingham offspring population. Circulation 2000;102:1634-38.

  188. Kim KS, Owen WL, Williams D, Adams-Campbell LL. A comparison between bmi and conicity index on predicting coronary heart disease: the Framingham Heart Study. Ann Epidemiol 2000;10:424-31.

  189. Zhang Y, Cupples LA, Rosenberg L, Colton T, Kreger BE. Parental ages at birth in relation to a daughter's risk of breast cancer among female participants in teh Framingham Study. Cancer Causes Control 1995;6:23-29.

  190. Cupples LA, Weinberg J, Beiser A, Auerbach SH, Volicer L, Cipolloni PB et al. Effects of smoking, alcohol and apoe genotype on alzheimer disease: the mirage study. Alzheimer's Reports 2000;3:105-14.

  191. Culleton BF, Larson MG, Parfrey PS, Kannel WB, Levy D. Proteinuria as a risk factor for cardiovascular disease and mortality in older people: a prospective study. Am J Med 2000;109:1-8.

  192. Beiser A, D'Agostino RB, Seshadri S, Sullivan LM, Wolf PA. Computing estimates of incidence, including lifetime risk: alzheimer's disease in the Framingham Study. the practical incidence estimators (PIE) macro. Stat Med 2000;19:1495-522.

  193. Elias MF, Beiser A, Wolf PA, Au R, White RF, D'Agostino RB. The preclinical phase of alzheimer disease - a 22-year prospective study of the Framingham cohort. Arch Neurol 2000;57:808-13.

  194. Lloyd-Jones DM, Evans JC, Larson MG, O'Donnell CJ, Roccella EJ, Levy D. Differential control of systolic and diastolic blood pressure: factors associated with lack of blood pressure control in the community. Hypertension 2000;36:594-99.

  195. Singh JP, Larson MG, O'Donnell CJ, Wilson PF, Tsuji H, Lloyd-Jones DM et al. Association of hyperglycemia with reduced heart rate variability: the Framingham Heart Study. Am J Cardiol 2000;86:309-12.

  196. Shearman AM, Ordovas JM, Cupples LA, Schaefer EJ, Harmon MD, Shao Y et al. Evidence for a gene influencing the TG/HDL-C ratio on chromosome 7q32.3-qter: a genome-wide scan in the Framingham Study. Hum Mol Genet 2000;9:1315-20.

  197. Moore LL, Visioni AJ, Wilson PWF, D'Agostino RB, Finkle WD, Ellison RC. Can sustained weight loss in overweight individuals reduce the risk of diabetes mellitus? Epidemiology 2000;11:269-73.

  198. Meigs JB, Ordovas JM, Cupples LA, Singer DE, Nathan DM, Schaefer EJ et al. Apolipoprotein e isoform polymorphisms are not associated with insulin resistance. Diabetes Care 2000;23:669-74.

  199. Hannan MT, Tucker KL, Dawson-Hughes B, Cupples LA, Felson DT, IH. Effect of dietary protein on bone loss in elderly men and women: the Framingham Osteoporosis study. J Bone Min Res 2000;15:2504-12.

  200. Chen L, Chen MH, Larson MG, Evans J, Benjamin EJ, Levy D. Risk factors for syncope in a community-based sample (The Framingham Heart Study). Am J Cardiol 2000;85:1189-93.

  201. Ordovas JM, Cupples LA, Corella D, Otvos JD, Osgood D, Martinez A et al. Association of cholesteryl ester transfer protein-TaqIB polymorphism with variations in lipoprotein subclasses and coronary heart disease risk: The Framingham Study. Arterioscler Thromb Vasc Biol 2000;20:1323-29.

  202. Zhang YQ, Hannan MT, Chaisson CE, McAlindon TE, Evans SR, Aliabadi P et al. Bone mineral density and risk of incident and progressive radiographic knee osteoarthritis in women: the Framingham Study. J Rheumatol 2000;27:1032-37.

  203. McLean RR, Hannan MT, Epstein BE, Bouxsein ML, Cupples LA, Murabito J et al. Elderly cohort study subjects unable to return for follow-up have lower bone mass than those who can return. Am J Epidemiol 2000;151:689-92.

  204. Wilson PWF. Metabolic risk factors for coronary heart disease: current and future prospects. Curr Opin Cardiol 1999;14:176-85.

  205. Wilson PWF, Kannel WB, Silbershatz H, D'Agostino RB. Clustering of metabolic factors and coronary heart disease. Arch Intern Med 1999;159:1104-09.

  206. Kannel WB, Wilson PWF. Lipid control in the pre-satin era, In: Gaw A, Packard CJ, Shepherd J, editors. Statins the HMG CoA reductase inhibitors in perspective. London: Martin Dunitz; 2000. p. 21-33.

  207. Hiller R, Podgor MJ, Sperduto RD, Wilson PWF, Chew EY, D'Agostino RB. High intraocular pressure and survival: the Framingham Studies. Am J Ophthalmol 1999;128:440-45.

  208. Couture P, Otvos JD, Cupples LA, Wilson PWF, Schaefer EJ, Ordovas JM. Association of the A-204C polymorphism in the cholesterol 7 alpha-hydroxylase gene with variations in plasma low density lipoprotein cholesterol levels in the Framingham Offspring Study. J Lipid Res 1999;40:1883-89.

  209. Gates GA, Schmid P, Kujawa SG, Nam B, D'Agostino R. Longitudinal threshold changes in older men with audiometric notches. Hearing Research 2000;141:220-28.

  210. Couture P, Otvos JD, Cupples LA, Lahoz C, Wilson PWF, Schaefer EJ et al. Association of the C-514T polymorphism in the hepatic lipase gene with variations in lipoprotein subclass profiles: the Framingham Offspring Study. Arterioscler Thromb Vasc Biol 2000;20:815-22.

  211. Couture P, Otvos JD, Cupples LA, Wilson PWF, Schaefer EJ, Ordovas JM. Absence of association between genetic variation in the promoter of the microsomal triglyceride transfer protein gene and plasma lipoproteins in the Framingham Offspring Study. Atherosclerosis 1999;148:337-43.

  212. Kannel WB. Fifty years of Framingham Study contributions to understanding hypertension. J Hum Hypertension 2000;14:83-90.

  213. Booth SL, Tucker KL, Chen H, Hannan MT, Gagnon DR, Cupples LA et al. Dietary vitamin k intakes are associated with hip fracture but no with bone mineral density in elderly men and women. Am J Clin Nutr 2000;71:1201-08.

  214. Kannel WB. Vital epidemiologic clues in heart failure. J Clin Epidemiol 2000;53:229-35.

  215. D'Agostino RB, Russell MW, Huse DM, Ellison RC, Silbershatz H, Wilson PWF et al. Primary and subsequent coronary risk appraisal: new results from the Framingham Study. Am Heart J 2000;139:272-81.

  216. Edmond SL, Felson DT. Prevalence of back symptoms in elders. J Rheumatol 2000;27:220-25.

  217. Franklin SS. Ageing and hypertension: the assessment of blood pressure indices in predicting coronary heart disease. J Hypertens 1999;17:S29-S36.

  218. Kannel WB. Risk stratification in hypertension: new insights from the Framingham Study. Am J Hypertension 2000;13:3S-10S.

  219. Poli KA, Tofler GH, Larson MG, Evans JC, Sutherland PA, Lipinska I et al. Association of blood pressure with fibrinolytic potential in the Framingham Offspring Population. Circulation 2000;101:264-69.

  220. Port S, Demer L, Jennrich R, Walter D, Garfinkel A. Systolic blood pressure and mortality. The Lancet 2000;355:175-80.

  221. Tucker KL, Rich S, Rosenberg I, Jacques P, Dallal G, Wilson PWF et al. Plasma vitamin B-12 concentrations relate to intake source in the Framingham Offspring Study. Am J Clin Nutr 2000;71:514-22.

  222. Kannel WB. Elevated systolic blood pressure as a cardiovascular risk factor. Am J Cardiol 2000;85:251-55.

  223. Meigs JB, Mittleman MA, Nathan DM, Tofler GH, Singer DE, Murphy-Sheehy PM et al. Hyperinsulinemia, hyperglycemia, and impaired hemostasis: the Framingham Offspring Study. JAMA 2000;283:221-28.

  224. Albert PS. A mover-stayer model for longitudinal marker data. Biometrics 1999;55:1252-57.

Years 1990-1999

  1. Kastelein, J. J. P., Ordovas, J. M., Wittekoek, M. E., Pimstone, S. N., Wilson, P. W. F., Gagne, S. E., Larson, M. G., Schaefer, E. J., Boer, J. M. A., Gerdes, C., and Hayden, M. R. Two common mutaions (D9N, N291S) in lipoprotein lipase: a cumulative analysis of their influence on plasma lipids and lipoproteins in men and women. Clin Genet 56(4), 297-305. 1999.
    Ref Type: Journal (Full)

  2. Culleton, B. F., Larson, M. G., Wilson, P. W. F., Evans, J. C., Parfrey, P. S., and Levy, D. Cardiovascular disease and mortality in a community-based cohort with mild renal insufficiency. Kidney International 56(6), 2214-2219. 1999.
    Ref Type: Journal (Full)

  3. Zhang, Y., Kreger, B. E., Dorgan, J. F., Cupples, L. A., Myers, R. H., Splansky, G. L., Schatzkin, A., and Ellison, R. C. Parental age at child's birth and son's risk of prostate cancer: The Framingham Study. Am J Epidemiol 150, 1208-1212. 1999.
    Ref Type: Journal (Full)

  4. Guidry, U. C., Evans, J. C., Larson, M. G., Wilson, P. W. F., Murabito, J. M., and Levy, D. Temporal trends in even rates after q-wave myocardial infarction. Circulation 100, 2054-2059. 1999.
    Ref Type: Journal (Full)

  5. Allaire, S. H., LaValley, M. P., Evans, S. R., O'Conner, G. T., Kelly-Hayes, M., Meenan, R. F., Levy, D., and Felson, D. T. Evidence for decline in disability and improved health among persons aged 55 to 70 years: The Framingham Heart Study. Am J Public Health 89, 1678-1683. 1999.
    Ref Type: Journal (Full)

  6. Lloyd-Jones, D. M., Evans, J. C., Larson, M. G., O'Donnell, C. J., Wilson, P. W. F., and Levy, D. Cross-classification of JNC VI blood pressure stages and risk groups in the Framingham Heart Study. Arch Intern Med 159, 2206-2212. 1999.
    Ref Type: Journal (Full)

  7. Kannel, W. B. Historic perspectives on the relative contributions of diastolic and systolic blood pressure elevation to cardiovascular risk profile. Amer Heart J 138(3), S205-S210. 1999.
    Ref Type: Journal (Full)

  8. Culleton, B. F., Larson, M. G., Evans, J. C., Wilson, P. W. F., Barrett, B. J., Parfey, P. S., and Levy, D. Prevalence and correlates of elevated serum creatinine levels. Arch Intern Med 159, 1785-1790. 1999.
    Ref Type: Journal (Full)

  9. Bostom, A. G., Rosenberg, I. H., Silbershatz, H., Jacques, P. F., Selhub, J., D'Agostino, R. B., Wilson, P. W. F., and Wolf, P. A. Nonfasting plasma total homocysteine levels and stroke incidence in elderly persons: the Framingham Study. Ann Intern Med 131(5), 352-355. 1999.
    Ref Type: Journal (Full)

  10. Clarke, R., Shipley, M., Lewington, S., Youngman, L., Collins, R., Marmot, M., and Peto, R. Underestimation of risk associations due to regression dilution in long-term follow-up of prospective studies. Amer J Epidemiol 150, 341-353. 1999.
    Ref Type: Journal (Full)

  11. Elias, P. K., Elias, M. F., D'Agostino, R. B., Silbershatz, H., and Wolf, P. A. Alcohol consumption and cognitive performance in the Framingham Heart Study. Am J Epidemiol 150, 580-589. 1999.
    Ref Type: Journal (Full)

  12. Lloyd-Jones DM, Evans JC, Larson MG, O'Donnell CJ, Levy D. Differential impact of systolic and diastolic blood pressure level on JNC-VI staging. Hypertension 1999;34:381-85.

  13. Freed LA, Levy D, Levine RA, Larson MG, Evans JC, Fuller DL et al. Prevalence and clinical outcome of mitral-valve prolapse. N Engl J Med 1999;341:1-7.

  14. Franklin SS. Cardiovascular risk related to increased diastolic, systolic and pulse pressure: the epidemiologist's point of view. Path Biol 1999;47:594-603.

  15. Allison DB, Zannolli R, Faith MS, Heo M, Pietrobelli A, VanItallie TB et al. Weight loss increases and fat loss decreases all-cause mortality rate: results from two independent cohort studies. Int J Obesity 1999;23:603-11.

  16. Gates GA, Couropmitree NN, Myers RH. Genetic associations in age-related hearing thesholds. Arch Otolaryngol Head Neck Surg 1999;125:654-59.

  17. Kannel WB, D'Agostino RB, Silbershatz H, Belanger AJ, Wilson PWF, Levy D. Profile for estimating risk of heart failure. Arch Intern Med 1999;159:1197-204.

  18. Bostom AG, Silbershatz H, Rosenberg IH, Selhub J, D'Agostino RB, Wolf PA et al. Nonfasting plasma total homocysteine levels and all-cause and cardiovascular disease mortality in elderly Framingham men and women. Arch Intern Med 1999;159:1077-80.

  19. Lauer MS, Larson MG, Evans JC, Levy D. Association of left ventricular dilation and hypertrophy with chronotropic incompetence in the Framingham Heart Study. Am Heart J 1999;137:903-09.

  20. Wilson PWF. Diabetes mellitus and coronary heart disease. Am J Kidney Dis 1998;32:S89-S100.

  21. Visser M, Harris TB, Langlois J, Hannan MT, Roubenoff R, Felson DT et al. Body fat and skeletal muscle mass in relation to physical disability in very old men and women of the Framingham Heart Study. J Gerontol 1998;53A:M214-M221.

  22. Wilson PWF, D'Agostino RB, Kannel WB. Secular trends in cardiovascular risk factor levels: a Framingham perspective, In: Jacotot B, Mathe D, Fruchart JC, editors. Atherosclerosis XI.Elsevier; 1998. p. 659-64.

  23. Ordovas JM, Cupples LA, Wilson PWF, Lahoz C, Levy D, Otvos JD et al. Advances in cardiovascular risk prediction: new biochemical and genetic markers, In: Jacotot B, Mathe D, Fruchart JC, editors. Atherosclerosis XI.Elsevier; 1998. p. 425-31.

  24. Kannel WB. Unrecognized myocardial infarction, In: Stern S, editor. Silent Myocardial Ischemia. London: Martin Dunitz Ltd; 1998. p. 47-53.

  25. Kannel WB. Epidemiologic insights into progression from hypertension to heart failure, In: Bohm M, Laragh JH, Manfred Z, editors. From Hypertension to Heart Failure.Springer-Verlag; 1998. p. 3-12.

  26. Wilson PWF, Kannel WB. Clustering of risk factors, obesity, and syndrome X. Nutr Clin Care 1999;1:44-50.

  27. Liao YL, McGee DL, Cooper RS, Sutkowski MBE. How generalizable are coronary risk prediction models? Comparison of Framingham and two national cohorts. Am Heart J 1999;137:837-45.

  28. Jacques PF, Selhub J, Bostom AG, Wilson PWF, Rosenberg IH. The effect of folic acid fortification on plasma folate and total homocysteine concentrations. N Engl J Med 1999;340:1449-54.

  29. Butler RN. Framingham: the town with heart - after 51 years, landmark study continues to teach us about cardiovascular disease. Geriatrics 1999;54:3-4.

  30. Feng DL, Lindpaintner K, Larson MG, Rao VS, O'Donnell CJ, Lipinska I et al. Increased platelet aggregability associated with platelet GPIIIa PI(A2) polymorphism - the Framingham Offspring Study. Arterioscler Thromb Vasc Biol 1999;19:1142-47.

  31. Tucker KL, Hannan MT, Chen H, Cupples LA, Wilson PWF, Kiel DP. Potassium, magnesium, and fruit and vegetable intakes are associated with greater bone mineral density in elderly men and women. Am J Clin Nutr 1999;69:727-36.

  32. Culleton BF, Larson MG, Kannel WB, Levy D. Serum uric acid and risk for cardiovascular disease and death: the Framingham Heart Study. Ann Intern Med 1999;131:7-13.

  33. Seman LJ, DeLuca C, Jenner JL, Cupples LA, McNamara JR, Wilson PWF et al. Lipoprotein(a)-cholesterol and coronary heart disease in the Framingham Heart Study. Clin Chem 1999;45:1039-46.

  34. Gagne SE, Larson MG, Pimstone SN, Schaefer EJ, Kastelein JJP, Wilson PWF et al. A common truncation variant of lipoprotein lipase (Ser447X) confers protection against coronary heart disease: the Framingham Offspring Study. Clin Genet 1999;55:450-54.

  35. Wilson PWF. Physical activity and coronary heart disease, In: Robinson K, editor. Preventive Cardiology. Armonk: Futura Pub Co; 1998. p. 51-67.

  36. Thom TJ, Kannel WB, Silbershatz H, D'Agostino RB. Incidence, prevalence, and mortality of cardiovascular diseases in the United States, In: Alexander RW, Schlant RC, Fuster V, editors. Hurst's the Heart, 9th ed.McGraw Hill; 1998. p. 3-17.

  37. Fraenkel L, Zhang YQ, Chaisson CE, Maricq HR, Evans SR, Brand F et al. Different factors influencing the expression of Raynaud's phenomenon in men and women. Arthritis Rheum 1999;42:306-10.

  38. Franklin SS, Khan SA, Wong ND, Larson MG, Levy D. Is pulse pressure useful in predicting risk for coronary heart disease? The Framingham Heart Study. Circulation 1999;100:354-60.

  39. Vaccarino V, Krumholz HM. Risk factors for cardiovascular disease: one down, many more to evaluate. Ann Intern Med 1999;131:62-63.

  40. Zhang Y, McAlindon TE, Hannan MT, Chaisson CE, Klein R, Wilson PWF et al. Estrogen replacement therapy and worsening of radiographic knee osteoarthritis. Arthritis Rheum 1998;41:1867-73.

  41. Wilson PWF. Diabetes mellitus, insulin resistance, and coronary heart disease, In: Robinson K, editor. Preventive Cardiology. Armonk: Futura Pub Co; 1998. p. 69-95.

  42. Kannel WB. Hypertension: epidemiological appraisal, In: Robinson K, editor. Preventive Cardiology. Armonk: Futura Publishing Co; 1998. p. 1-14.

  43. Fraenkel L, Zhang Y, Trippel SB, McAlindon TE, LaValley MP, Assif A et al. Longitudinal analysis of the relationship between serum insulin-like growth factor-I and radiographic knee osteoarthritis. Osteoarthritis Cart 1998;6:362-67.

  44. Zhang Y, Kreger BE, Dorgan JF, Splansky GL, Cupples LA, Ellison RC. Authors' response to "the Framingham results on alcohol and breast cancer". Am J Epidemiol 1999;149:105.

  45. Zhang Y, Kreger BE, Dorgan JF, Splansky GL, Cupples LA, Ellison RC. Alcohol consumption and risk of breast cancer: the Framingham Study. Am J Epidemiol 1999;149:93-101.

  46. Witteman JCM, D'Agostino RB, Stijnen T, Kannel WB, Cobb JC, de Ridder MAJ et al. G-estimation of causal effects: isolated systolic hypertension and cardiovascular death in the Framingham Heart Study. Am J Epidemiol 1998;148:390-401.

  47. Wilson PWF. Do estrogens reduce glycemic levels? Diabetes Care 1998;21:1585.

  48. Redline S, Sanders MH, Lind BK, Quan SF, Iber C, Gottlieb DJ et al. Methods for obtaining and analyzing unattended polysomnography data for a multicenter study. Sleep 1998;21:759-67.

  49. Langlois JA, Rosen CJ, Visser M, Hannan MT, Harris T, Wilson PWF et al. Association between insulin-like growth factor-I and bone mineral density in older women and men: the Framingham Heart Study. J Clin Endocrinol Metab 1998;83:4257-62.

  50. Kauppila LI, Eustace S, Kiel DP, Felson DT, Wright AM. Degenerative displacement of lumbar vertebrae. Spine 1998;23:1868-74.

  51. Kannel WB, Wilson PWF, D'Agostino RB, Cobb J. Sudden coronary death in women. Am Heart J 1998;136:205-12.

  52. Kannel WB. Overview of atherosclerosis. Clin Ther 1998;20:B2-B17.

  53. Hiller R, Podgor MJ, Sperduto RD, Nowroozi L, Wilson PWF, D'Agostino RB et al. A longitudinal study of body mass index and lens opacities: the Framingham Studies. Ophthalmol 1998;105:1244-50.

  54. Fraenkel L, Roubenoff R, LaValley M, McAlindon T, Chaisson C, Evans S et al. The association of peripheral monocyte derived interleukin 1B (IL-1B), IL-1 receptor antagonist, and tumor necrosis factor-a with osteoarthritis in the elderly. J Rheumatol 1998;25:1820-26.

  55. Wolf PA. Prevention of Stroke. Lancet 1998;352:SIII15-SIII18.

  56. Wijman CAC, Wolf PA, Kase CS, Kelly-Hayes M, Beiser AS. Migrainous visual accompaniments are not rare in late life: the Framingham Study. Stroke 1998;29:1539-43.

  57. Welty FK, Lahoz C, Tucker KL, Ordovas JM, Wilson PWF, Schaefer EJ. Frequency of ApoB and ApoE gene mutations as causes of hypobetalipoproteinemia in the Framingham Offspring population. Arterioscler Thromb Vasc Biol 1998;18:1745-51.

  58. Brand FN, Kannel WB, Evans J, Larson MG, Wolf PA. Glucose intolerance,physical signs of peripheral artery disease, and risk of cardiovascular events: the Framingham Study. Amer Heart J 1998;136:919-27.

  59. Tucker KL, Chen H, Vogel S, Wilson PWF, Schaefer EJ, Lammi-Keefe CJ. Carotenoid intakes, assessed by dietary questionnaire, are associated with plasma carotenoid concentrations in an elderly population. J Nutr 1999;129:438-45.

  60. McNamara JR, Shah PK, Nakajima K, Cupples LA, Wilson PWF, Ordovas JM et al. Remnant lipoprotein cholesterol and triglyceride reference ranges from the Framingham Heart Study. Clin Chem 1998;44:1224-32.

  61. McAlindon TE, Wilson PWF, Aliabadi P, Weissman B, Felson DT. Level of physical activity and the risk of radiographic and symptomatic knee osteoarthritis in the elderly: the Framingham Study. Am J Med 1999;106:151-57.

  62. Kannel WB, Wolf PA, Benjamin EJ, Levy D. Prevalence, incidence, prognosis, and predisposing conditions for atrial fibrillation: population-based estimates. Am J Cardiol 1998;82:2N-9N.

  63. Kannel WB. The worth of controlling plasma lipids. Am J Cardiol 1998;81:1047-49.

  64. Gottlieb DJ, Whitney CW, Bonekat WH, Iber C, James GD, Lebowitz M et al. Relation of sleepiness to respiratory disturbance index. Am J Respir Crit Care Med 1999;159:502-07.

  65. Wilson PWF, Culleton BF. Epidemiology of cardiovascular disease in the United States. Am J Kidney Dis 1998;32:S56-S65.

  66. Vasan RS, Larson MG, Benjamin EJ, Evans JC, Reiss CK, Levy D. Congestive heart failure in subjects with normal versus reduced left ventricle ejection fraction: prevalence and mortality in a population-based cohort. J Am Coll Cardiol 1999;33:1948-55.

  67. Singh JP, Larson MG, Manolio TA, O'Donnell CJ, Lauer M, Evans JC et al. Blood pressure response during treadmill testing as a risk factor for new-onset hypertension: the Framingham Heart Study. Circulation 1999;99:1831-36.

  68. Singh JP, Larson MG, O'Donnell CJ, Tsuji H, Evans JC, Levy D. Heritability of heart rate variability: the Framingham Heart Study. Circulation 1999;99:2251-54.

  69. Singh JP, Evans JC, Levy D, Larson MG, Freed LA, Fuller DL et al. Prevalence and clinical determinants of mitral, tricuspid, and aortic regurgitation (the Framingham Heart Study). Am J Cardiol 1999;83:897-902.

  70. Norman JE, Bailey JJ, Berson AS, Haisty WK, Levy D, Macfarlane PM et al. NHLBI workshop on the utilization of ECG databases. J Electrocardiol 1998;31:83-89.

  71. Lloyd-Jones DM, Martin DO, Larson MG, Levy D. Accuracy of death certificates for coding coronary heart disease as the cause of death. Ann Intern Med 1998;129:1020-26.

  72. Lloyd-Jones DM, Larson MG, Beiser A, Levy D. Lifetime risk of developing coronary heart disease. Lancet 1999;353:89-92.

  73. Levy D. The role of systolic blood pressure in determining risk for cardiovascular disease. J Hypertens 1999;17:S15-S18.

  74. Levy D, Thom TJ. Death rates from coronary disease - progress and a puzzling paradox. N Engl J Med 1998;339:915-17.

  75. Himmelmann A, Hedner T, Hansson L, O'Donnell CJ, Levy D. Isolated systolic hypertension: an important cardiovascular risk factor. Blood Pressure 1998;7:197-207.

  76. Haider AW, Larson MG, O'Donnell CJ, Evans JC, Wilson PWF, Levy D. The association of chronic cough with the risk of myocardial infarctionn: the Framingham Heart Study. Am J Med 1999;106:279-84.

  77. Haider AW, Larson MG, Benjamin EJ, Levy D. Increased left ventricle mass and hypertrophy are associated with increased risk for sudden death. J Am Coll Cardiol 1998;32:1454-59.

  78. Givelber RJ, Couropmitree NN, Gottlieb DJ, Evans JC, Levy D, Myers RH et al. Segregation analysis of pulmonary function among families in the Framingham Study. Am J Respir Crit Care Med 1998;157:1445-51.

  79. Fraenkel L, Zhang Y, Chaisson CE, Evans SR, Wilson PWF, Felson DT. The association of estrogen replacement therapy and the Raynaud phenomenon in postmenopausal women. Ann Intern Med 1998;129:208-11.

  80. Felson DT, Couropmitree NN, Chaisson CE, Hannan MT, Zhang Y, McAlindon TE et al. Evidence for a Mendelian gene in a segregation analysis of generalized radiographic osteoarthritis. Athritis Rheum 1998;41:1064-71.

  81. Culleton BF, Wilson PWF. Cardiovascular disease: risk factors, secular trends, and therapeutic guidelines. J Am Soc Nephrol 1998;9:S5-S15.

  82. Chaisson CE, Zhang Y, Sharma L, Kannel W, Felson DT. Grip strength and the risk of developing radiographic hand osteoarthritis - results from the Framingham Study. Arthritis Rheum 1999;42:33-38.

  83. Benjamin EJ, Levy D. Why is left ventricular hypertrophy so predictive of morbidity and mortality? Am J Med Sci 1999;317:168-75.

  84. Benjamin EJ, Wolf PA, D'Agostino RB, Silbershatz H, Kannel WB, Levy D. Impact of atrial fibrillation on the risk of death: The Framingham Heart Study. Circulation 1998;98:946-52.

  85. Abascal VM, Larson MG, Evans JC, Blohm AT, Poli K, Levy D. Calcium antagonists and mortality risk in men and women with hypertension in the Framingham Heart Study. Arch Intern Med 1998;158:1882-86.

  86. Gresham GE, Kelly-Hayes M, Wolf PA, Beiser AS, Kase CS, D'Agostino RB. Survival and functional status 20 or more years after first stroke: The Framingham Study. Stroke 1998;29:793-97.

  87. Zhang Y, Kiel DP, Kreger BE, Cupples LA, Ellison RC, Dorgan JF et al. Bone mass and the risk of breast cancer among postmenopausal women. N Engl J Med 1997;336:611-17.

  88. Wolf PA. Cerebrovascular disease: Precursors and prevention. Jpn J Stroke 1997;19:87-97.

  89. Wolf PA, Singer DE. Preventing stroke in atrial fibrillation. Am Fam Physician 1997;56:2242-50.

  90. Wilson PWF, Kannel WB. Should we measure Lipoprotein Lp(a)? Arch Intern Med 1997;157:1161-62.

  91. Wilson PWF. An epidemiologic perspective of systemic hypertension, ischemic heart disease,heart failure. Am J Cardiol 1997;80:3J-8J.

  92. Vogel S, Contois JH, Tucker KL, Wilson PWF, Schaefer EJ, Lammi-Keefe CJ. Plasma retinol and plasma and lipoprotein tocopherol and carotenoid concentrations in healthy elderly participants of the The Framingham Heart Study. Am J Clin Nutr 1997;66:950-58.

  93. Visser M, Kiel DP, Langlois J, Hannan MT, Felson DT, Wilson PWF et al. Muscle mass and fat mass in relation to bone mineral density in very old men and women:The Framingham Heart Study. Appl Radiat Isot 1998;49:745-47.

  94. Vasan RS, Levy D. The progression from hypertension to heart failure:an overview of pathogenetic mechanisms, In: Coats A, editor. Controversies in the Management of Heart Failure. New York: Churchill Livingstone; 1997. p. 1-10.

  95. Vasan RS, Larson MG, Levy D, Evans JC, Benjamin EJ. Distribution and categorization of echocardiographic measurements in relation to reference limits:The Framingham Heart Study:formulation of a height-and sex-specific classification and its prospective validation. Circulation 1997;96:1863-73.

  96. Vasan RS, Larson MG, Benjamin EJ, Evans JC, Levy D. Left venticular dilation and the risk of congestive heart failure in people without myocardial infraction. N Engl J Med 1997;336:1350-55.

  97. Seshadri S, Wolf PA, Beiser A, Au R, McNulty K, White R et al. Lifetime risk of dementia and Alzheimer's disease:the impact of mortality on risk estimates in the Framingham Study. Neurology 1997;49:1498-504.

  98. O'Donnell CJ, Lindpaintner K, Larson MG, Rao VS, Ordovas JM, Schaefer EJ et al. Evidence for association and genetic linkage of the angiotensin-converting enzyme locus with hypertension and blood pressure in men but not women in the Framingham Heart Study. Circulation 1998;97:1766-72.

  99. Roubenoff R, Harris TB. Failure to thrive, sarcopenia, and functional decline in the elderly. Clinics in Geriatric Medicine 1997;13:613-22.

  100. Roubenoff R, Harris TB, Abad LW, Wilson PWF, Dallal GE, Dinarello CA. Monocyte cytokine production in an elderly population:Effect of age and inflammation. J Gerontol 1998;53:M20-M26.

  101. Post WS, Larson MG, Myers RH, Galderisi M, Levy D. Heritability of left venticular mass:the Framingham Heart Study. Hypertension 1997;30:1025-28.

  102. Mosterd A, D'Agostino RB, Silbershatz H, Sytkowski PA, Kannel WB, Grobbee DE et al. Trends in the prevalence of hypertension, antihypertensive therapy, and left ventricular hypertrophy from 1950 to 1989. N Engl J Med 1999;340:1221-27.

  103. Norman JE, Levy D. Adjustment of ECG left venticular hypertrophy criteria for body mass index and age improves classification accuracy; the effects of hypertension and obesity. J Electrocardiol 1997;29:suppl 241-suppl 247.

  104. Murabito JM, D'Agostino RB, Silbershatz H, Wilson PWF. Intermittent claudication; a risk profile from the Framingham Heart Study. Circulation 1997;96:44-49.

  105. Meigs JB, D'Agostino RB, Wilson PWF, Cupples LA, Nathan DM, Singer DE. Risk variable clustering in the insulin resistance syndrome:The Framingham Offspring Study. Diabetes 1997;46:1594-600.

  106. McAlindon T, Felson DT. Nutrition:risk factors for osteoarthritis. Annals of the Rheumatic Diseases 1997;56:397-402.

  107. Levy D, Wilson PWF. Atherosclerotic cardiovascular disease:an epidemiologic perspective, In: Topol EJ, editor. Text of Cardiovascular Medicine. Philadelphia: Lippincott-Raven; 1998. p. 13-30.

  108. Lauer MS, Pashkow FJ, Larson MG, Levy D. Association of cigarette smoking with chronotropic incompetence and prognosis in the Framingham Heart Study. Circulation 1997;96:897-903.

  109. Krall EA, Dawson-Hughes B, Hannan MT, Wilson PWF, Kiel DP. Postmenopausal estrogen replacement and tooth retention. Am J Med 1997;102:536-42.

  110. Meigs JB, Nathan DM, Wilson PWF, Cupples LA, Singer DE. Metabolic risk factors worsen continuously across the spectrum of nondiabetic glucose tolerance. Ann Intern Med 1998;128:524-33.

  111. Wilson PWF, D'Agostino RB, Levy D, Belanger AM, Silbershatz H, Kannel WB. Prediction of coronary heart disease using risk factor categories. Circulation 1998;97:1837-47.

  112. Kiel DP, Myers RH, Cupples LA, Kong XF, Zhu XH, Ordovas J et al. The BsmI vitamin D receptor restriction fragment length polymorphism(bb) influences the effect of calcium intake on bone mineral density. J Bone Miner Res 1997;12:1049-57.

  113. Kauppila LI, Polak J, Cupples LA, Hannan MT, Kiel DP, Wilson PWF. New indices to classify location, severity and progression of calcific lesions in the abdominal aorta:a 25-year follow-up study. Atherosclerosis 1997;132:245-50.

  114. Kauppila LI, McAlindon T, Evans S, Wilson PWF, Kiel D, Felson DT. Disc degeneration/back pain and calification of the abdominal aorta:A 25-year follow-up study in Framingham. Spine 1997;22:1642-49.

  115. Kannel WB. Influence of fibrinogen on cardiovascular disease. Drugs 1997;54:32-40.

  116. Kannel WB. Effect of weight on cardiovascular disease. Nutrition 1997;13:157-58.

  117. Kannel WB. Curbing the tobacco menace. Circulation 1997;96:1070.

  118. Kannel WB. Cardiovascular risk factors in the elderly. Coronary Artery Disease 1997;8:565-75.

  119. Kannel WB, D'Agostino RB, Silbershatz H. Blood pressure and cardiovascular morbidity and mortality rates in the elderly. Am Heart J 1997;134:758-63.

  120. Jacques PF, Felson DT, Tucker KL, Mahnken B, Wilson PWF, Rosenberg IH et al. Plasma 25-hydroxyvitamin D and its determinants in an elderly population sample. Am J Clin Nutr 1997;66:929-36.

  121. Ho KKL, Moody GB, Chung-Kang P, Mietus JE, Larson MG, Levy D et al. Predicting survival in heart failure case and control subjects by use of fully automated methods for deriving nonlinear and conventional indices of heart rate dynamics. Circulation 1997;96:842-48.

  122. Hiller R, Sperduto RD, Podgor MJ, Wilson PWF, Ferris FL, Colton T et al. Cigarette smoking and the risk of development of lens opacities, The Framingham Studies. Arch Ophthalmol 1997;115:1113-18.

  123. Singh JP, Larson MG, Tsuji H, Evans JC, O'Donnell CJ, Levy D. Reduced heart rate variability and new-onset hypertension: insight into pathogenesis of hypertension: the Framingham Heart Study. Hypertension 1998;32:293-97.

  124. Haider AW, Chen L, Larson MG, Evans JC, Chen MH, Levy D. Antecedent hypertension confers increased risk for adverse outcomes after initial myocardial infarction. Hypertension 1997;30:1020-24.

  125. Gillman MW, Cupples LA, Millen BE, Ellison RC, Wolf PA. Inverse association of dietary fat with development of ischemic stroke in men. JAMA 1997;278:2145-50.

  126. Gillman MW, Cupples LA, Gagnon DR, Millen BE, Ellison RC, Castelli WP. Margarine intake and subsequent coronary heart disease in men. Epidemiology 1997;8:144-49.

  127. Franklin SS, Gustin IV W, Wong ND, Larson MG, Weber MA, Kannel WB et al. Hemodynamic patterns of age-related changes in blood pressure. Circulation 1997;96:308-15.

  128. Felson DT, McAlindon TE, Anderson JJ, Naimark A, Weissman BW, Aliabadi P et al. Defining radiographic osteoarthritis for the whole knee. Osteoarthritis and Cartilage 1997;5:241-50.

  129. Farrer LA, Cupples LA, Kukill WA, Volicer L, Wells JM, Kurz A et al. Risk of Alzheimer disease is associated with parental age among apolipoprotein E 4 heterozygotes. Alzheimer's Research 1997;3:83-91.

  130. Elias MF, Elias PK, D'Agostino RB, Silbershatz H, Wolf PA. Role of age, education, and gender on cognitive performance in the Framingham Heart Study:Community-based norms. Experimental Aging Research 1997;23:201-35.

  131. Ekery D, Benjamin EJ. Cardiac disease and stroke:Innocent bystander or cause and effect. Compr Ther 1997;23:281-88.

  132. Chaisson CE, Zhang Y, McAlindon TE, Hannan MT, Aliabadi P, Naimark A et al. Radiographic hand osteoarthritis:incidence, patterns and influence of pre-existing disease in a population based sample. J Rheumatol 1997;24:1337-43.

  133. Brand FN, Larson MG, Kannel WB, McGuirk JM. The occurrence of Raynaud's phenomenon in a general population:the Framingham Study. Vascular Med 1997;2:296-301.

  134. Cupples LA, Gagnon DR, Ramaswamy R, D'Agostino RB. Age-adjusted survival curves with application in the Framingham Heart Study. Stat Med 1995;14:1731-44.

  135. Siguel E. A new relationship between total/high density lipoprotein cholesterol and polyunsaturated fatty acids. Lipids 1996;31:S-51-S-56.

  136. Brand FN, Larson M, Friedman LM, Kannel WB, Castelli WP. Epidemiologic assesment of angina before and after myocardial infarction: The Framingham Study. Am Heart J 1996;132:174-78.

  137. Elias PK, Elias MF, D'Agostino RB, Cupples LA, Wilson PWF, Silbershatz H et al. NIDDM and blood pressure as risk factors poor cognitive performance. Diabetes Care 1997;20:1388-95.

  138. Voelker R. Two generations of data aid Framingham's focus on genes. JAMA 1998;279:1245-46.

  139. Garber AM, Browner WS, Hulley SB. Cholesterol screening in asymptomatic adults, revisited. Ann Intern Med 1996;124:518-31.

  140. Kelly-Hayes M, Wolf PA, Kase CS, Brand FN, McGuirk JM, D'Agostino RB. Temporal patterns of stroke onset, The Framingham Study. Stroke 1995;26:1343-47.

  141. Herrera CR, D'Agostino RB, Gerstman BB, Bosco LA, Belanger AJ. Baldness and coronarry heart disease rates in men from the Framingham Study. Am J Epidemiol 1995;142:828-33.

  142. Meigs JB, Nathan DM, Cupples LA, Wilson PWF, Singer DE. Tracking of glycated hemoglobin in the original cohort of the Framingham Heart Study. J Clin Epidemiol 1996;44:411-17.

  143. Kase CS, Wolf PA, Kelly-Hayes M, Kannel WB, Beiser A, D'Agostino RB. Intellectual decline after stroke, The Framingham Study. Stroke 1998;29:805-12.

  144. Bostom AG, Shemin D, Lapane KL, Sutherland P, Nadeau M, Wilson PWF et al. Hyperhomocysteinemia, hyperfibrinogenemia, and lipoprotein (a) excess in maintance dialysis patiennts: a matched case-control study. Atherosclerosis 1996;125:91-101.

  145. Sharp SJ, Pocock SJ. Time trends in serum cholesterol before cancer death. Epidemiology 1997;8:132-36.

  146. Levy D, Sprecher DL. Preventive cardiology: Whose job is it? Who will pay for it? What is the best strategy? Cleve Clin J Med 1996;63:275-79.

  147. McAlindon TE, Felson DT, Zhang Y, Hannan MT, Aliabadi P, Weissman B et al. Relation of dietary intake and serum levels of vitamin D to progression of osteoarthritis of the knee among participants in the Framingham Study. Ann Intern Med 1996;125:353-59.

  148. Fleming DJ, Jacques PF, Dallal GE, Tucker KL, Wilson PWF, Wood RJ. Dietary determinants of iron stores in a free-living elderly population: The Framingham Heart Study. Am J Clin Nutr 1998;67:722-33.

  149. Ludwig EH, Borecki IB, Ellison RC, Folsom AR, Heiss G, Higgins M et al. Association between candidate loci angiotensin-converting enzyme and angiotensinogen with coronary heart disease and myocardial infarction: The NHLBI Family Heart Study. Ann Epidemiol 1997;7:3-12.

  150. Welty FK, Mittleman MA, Wilson PWF, Sutherland P, Matheney TH, Lipinska I et al. Hypobetalipoproteinemia is associated with low levels of hemostatic risk factors in the framingham offspring population. Circulation 1997;95:825-30.

  151. Felson DT, Zhang Y, Hannan MT, Naimark A, Weissman B, Aliabadi P et al. Risk factors for incident radiographic knee osteoarthritis in the elderly. Arthritis Rheum 1997;40:728-33.

  152. Emond MJ, Zareba W. Prognostic value of cholesterol in women of different ages. Journal of Women's Health 1997;6:295-307.

  153. Millen BE, Quatromoni PA, Franz MM, Epstein BE, Cupples AC, Copenhafer DL. Population nutrient intake approaches dietary recommendations: 1991 to 1995 Framingham nutrition studies. J Am Diet Assoc 1997;97:742-49.

  154. Roubenoff R, Baumgartner RN, Harris TB, Dallal GE, Hannan MT, Economos CD et al. Application of bioelectrical impedance analysis to elderly populations. J Gerontol 1997;52A:129-36.

  155. Harris TB, Kiel D, Roubenoff R, Langlois J, Hannan M, Havlik R et al. Association of insulin-like growth factor-I with body composition, weight history, and past health behaviors in the very old: The Framingham Heart Study. J Am Geriatr Soc 1997;45:133-39.

  156. Weaver MT, Mueller RO, Leighton R. Promoting wellness by delaying age of cardiovascular disease onset: development of a model. J Cardiovasc Nurs 1997;11:80-92.

  157. Demets D, Halperin M. Estimation of a simple regression coefficient in samples arising from a sub-sampling procedure. Biometrics 1977;33:47-56.

  158. Wilson PWF, Kannel WB. Should we measure lipoprotein Lp(a)? Arch.Intern.Med. 1997;157:1161-62.

  159. Wilson PWF, Hoeg JM, D'Agostino RB, Silbershatz H, Belanger AM, Poelhmann H et al. Cumulative effects of high cholesterol levels high blood pressure, and cigarette smoking on carotid stenosis. N Engl J Med 1997;337:516-22.

  160. Borecki IB, Province MA, Ludwig EH, Ellison RC, Folsom AR, Heiss G et al. Associations of candidate loci angiotensinogen and angiotensin-converting enzyme with severe hypertension: the NHLBI Family Heart Study. Ann Epidemiol 1997;7:13-21.

  161. Thom TJ, Kannel WB. Congestive heart failure: epidemiology and cost of illness. Dis Manage Health Outcomes 1997;2:75-83.

  162. Dowd JE, Manton KG. Forecasting chronic disease risks in developing countries. Int J Epidemiol 1990;19:1019-36.

  163. Tucker KL, Mahnken B, Wilson PWF, Jacques P, Selhub J. Folic acid fortification of the food supply: potential benefits and risks for the elderly population. JAMA 1996;276:1879-85.

  164. Sytkowski PA, D'Agostino RB, Belanger AJ, Kannel WB. Secular trends in long-term sustained hypertension, long-term treatment, and cardiovascular mortality. The Framingham Heart Study 1950 to 1990. Circulation 1996;93:697-703.

  165. Sytkowski PA, D'Agostino RB, Belanger A, Kannel WB. Sex and time trends in cardiovascular disease incidence and mortality: the Framingham Heart Study, 1950-1989. Am.J.Epidemiol. 1996;143:338-50.

  166. Gates GA, Cobb JL, Linn RT, Rees T, Wolf PA, D'Agostino RB. Central auditory dysfunction, cognitive dysfunction, and dementia in older people. Arch Otolaryngol Head Neck Surg 1996;122:161-67.

  167. Sonnenberg LM, Quatromoni PA, Gagnon DR, Cupples LA, Franz MM, Ordovas JM et al. Diet and plasma lipids in women. II. Macronutrients and plasma triglycerides, high-density lipoprotein, and the ratio of total to high-density lipoprotein cholesterol in women: the Framingham Nutrition Studies. J Clin Epidemiol 1996;49:665-72.

  168. Millen BE, Franz MM, Quatromoni PA, Gagnon DR, Sonnenberg LM, Ordovas JM et al. Diet and plasma lipids in women. I. Macronutrients and plasma total and low-density lipoprotein cholesterol in women: the Framingham nutrition studies. J Clin Epidemiol 1996;49:657-63.

  169. Contois JH, McNamara JR, Lammi-Keefe CJ, Wilson PWF, Massov T, Schaefer EJ. Reference intervals for plasma apolipoprotein B determined with a standardized commercial immunoturbidimetric assay: results from the Framingham Offspring Study. Clinical Chemistry 1996;42:515-23.

  170. Contois JH, McNamara JR, Lammi-Keefe CJ, Wilson PWF, Massov T, Schaefer EJ. Reference intervals for plasma apolipoprotein A-1 determined with a standardized commercial immunoturbidimetric assay: results from the Framingham Offspring Study. Clinical Chemistry 1996;42:507-14.

  171. Vasan RS, Levy D. The role of hypertension in the pathogenesis of heart failure: a clinical mechanistic overview. Arch Intern Med. 1996;156:1789-96.

  172. Tsuji H, Larson MG, Venditti FJ, Manders ES, Evans JC, Feldman CL et al. Impact of reduced heart rate variability on risk for cardiac events. The Framingham Heart Study. Circulation 1996;94:2850-55.

  173. Tsuji H, Venditti FJ, Manders ES, Evans JC, Larson MG, Feldman CL et al. Determinants of heart rate variability. J Am Coll Cardiol 1996;28:1539-46.

  174. Elias PK, D'Agostino RB, Elias MF, Wolf PA. Blood pressure, hypertension, and age as risk factors for poor cognitive performance. Experimental Aging Research 1995;21:393-417.

  175. Elias MF, D'Agostino RB, Elias PK, Wolf PA. Neuropsychological test performance, cognitive functioning, blood pressure, and age: the Framingham Heart Study. Experimental Aging Research 1995;21:369-91.

  176. Kannel WB. Framingham Study insights into hypertensive risk of cardiovascular disease. Hypertens Res 1995;18:181-96.

  177. Linn RT, Wolf PA, Bachman DL, Knoefel JE, Cobb JL, Belanger AJ et al. The 'preclinical phase' of probable Alzheimer's disease. A 13-year prospective study of the Framingham cohort. Arch.Neurol. 1995;52:485-90.

  178. White LR, Ordovas J, Schaefer EJ, Wilson PWF, Young SG. Identification and molecular analysis of two ApoB gene mutations causing low plasma cholesterol levels. Circulation 1995;95:2036-940.

  179. Posner BM, Franz MM, Quatromoni PA, Gagnon DR, Sytkowski PA, D'Agostino RB et al. Secular trends in diet and risk factors for cardiovascular disease: the Framingham Study. J Am Diet Assoc 1995;95:171-79.

  180. Bostom AG, Shemin D, Lapane KL, Miller JW, Sutherland P, Nadeau M et al. Hyperhomocysteinemia and traditional cardiovascular disease risk factors in end-stage renal disease patients on dialysis: a case-control study. Atherosclerosis 1995;114:93-103.

  181. Lin H, Wolf PA, Benjamin EJ, Belanger AJ, D'Agostino RB. Newly diagnosed atrial fibrillation and acute stroke. Stroke 1995;26:1527-30.

  182. Manton KG, Stallard E, Woodbury MA, Dowd JE. Time-varying covariates in models of human mortality and aging: multidimensional generalizations of the Gompertz. Journal of Gerontology: Biological Sciences 1994;B169-B190.

  183. Freund KM, Belanger AJ, D'Agostino RB, Kannel WB. The health risks of smoking. The Framingham Study: 34 years of follow-up. Ann Epidemiol 1993;3:417-24.

  184. Kannam JP, Levy D. Isolated sysytolic hypertension in the elderly. Hosp.Pract. 1993;57-74.

  185. Cooper JC, Gates GA. Central auditory processing disorders in the elderly: the effects of pure tone average and maximum word recognition. Ear Hear 1992;13:278-80.

  186. Devereux RB, Diodati JG, Levy D. Cardiac hypertrophy: practice implications. Patient Care 1992;88-122.

  187. Lauer MS, Levy D. Left ventricular hypertrophy: risk, clinical correlates, and therapeutic implications. Focus on Hypertension 1992;5-10.

  188. Milton RC, Sperduto RD, Ferris FL, Hiller R, Podgor MJ, Freidlin V et al. Associations of types of lens opacities between and within eyes of individuals: an application of second-order generalized estimating equations. Stat Med 1996;15:145-56.

  189. Kannel WB, Ellison RC. Alcohol and coronary heart disease: the evidence for a protective effect. Clinica Chimica Acta 1996;246:59-76.

  190. Lauer MS, Okin PM, Larson MG, Evans JC, Levy D. Impaired heart rate response to graded exercise: prognostic implications of chronotropic incompetence in the Framingham Heart Study. Circulation 1996;93:1520-26.

  191. Myers RH, Schaefer EJ, Wilson PWF, D'Agostino R, Ordovas JM, Espino A et al. Apolipoprotein E type 4 allele is associated with dementia in a population-based study: the Framingham Study. Neurology 1996;46:673-77.

  192. Vokonas PS, Kannel WB. Risk factors for and prevention of atherosclerotic cardiovascular disease, In: Sapira JD, Alpert JS, Bone RC, Korenman SG, editors. Current Practice of Medicine, vol. 1. New York: Churchill Livingstone; 1996. p. 7.1-7.10.

  193. Levy D, Lauer MS. Left ventricular hypertrophy: echocardiographic assessment and prognostic implications, In: Sutton MGStJ, Oldershaw PJ, Kotler MN, editors. Textbook of Echocardiography and Doppler in Adults and Children, 2 ed. Cambridge,MA: Blackwell Science; 1996. p. 342-52.

  194. Kannel WB. Epidemiologic relationship of disease among the different vascular territories, In: Fuster V, Ross R, Topol EJ, editors. Atherosclerosis and Coronary Artery Disease, vol. 2. Philadelphia: Lippincott-Raven; 1996. p. 1591-99.

  195. Wolf PA, Benjamin EJ, Belanger AJ, Kannel WB, Levy D, D'Agostino RB. Secular trends in the prevalence of atrial fibrillation: The Framingham Study. Am Heart J 1996;131:790-95.

  196. Kannel WB. Blood pressure as a cardiovascular risk factor. Prevention and treatment. JAMA 1996;275:1571-76.

  197. Kannel WB, Wilson PWF. Homocysteine, folate, and vascular disease. J Myocard Ischemia 1996;8:60-63.

  198. Lenfant C. Editorial. High blood pressure. Some answers, new questions, continuing challenges. JAMA 1996;275:1604-06.

  199. Levy D, Larson MG, Vasan RS, Kannel WB, Ho KKL. The progression from hypertension to congestive heart failure. JAMA 1996;275:1557-62.

  200. Lindpaintner K, Lee ML, Larson MG, Rao S, Pfeffer MA, Ordovas JM et al. Absence of association or genetic linkage between the angiotensin-converting-enzyme gene and left ventricular mass. N Engl J Med 1996;334:1023-28.

  201. Goldberg RJ, Larson M, Levy D. Factors associated with survival to 75 years of age in middle-aged men and women. Arch Intern Med 1996;156:505-09.

  202. Chen L, Benjamin EJ, Larson MG, Evans JC, Levy D. Doppler diastolic filling indexes in relation to disease states. Hypertension 1996;131:519-24.

  203. Lauer MS, Larson MG, Levy D. Gender-specific reference M-mode values in adults: population-derived values with consideration of the impact of height. J Am Coll Cardiol 1996;26:1039-46.

  204. Norman JE, Levy D. Improved electrocardiographic detection of echocardiographic left ventricular hypertrophy: results of a correlated data base approach. J Am Coll Cardiol 1996;26:1022-29.

  205. Cobb JL, Wolf PA, Au R, White R, D'Agostino RB. The effect of education on the incidence of dementia and Alzheimer's disease in the Framingham Study. Neurology 1995;45:1701-12.

  206. Benjamin EJ, D'Agostino RB, Belanger AJ, Wolf PA. Left atrial size and the risk of stroke and death. The Framingham Heart Study. Circulation 1995;92:835-41.

  207. Kannel WB. Current status of coronary risk factors. Excepta Medica 1995;21-28.

  208. Vokonas PS, Kannel WB. Diabetes mellitus and coronary heart disease in the elderly., In: Aronow WS, Tresch DD, editors. Clinics in Geriatric Medicine., 12 ed. Philadelphia: WB Saunders Co.; 1996. p. 69-78.

  209. Kannel WB. Need and prospects for prevention of cardiac failure. Eur J Clin Pharmacol 1996;49 Suppl:S3-S9.

  210. Kannel WB. Prevalence, incidence, and mortality of coronary heart disease., In: Fuster V, Ross R, Topol EJ, editors. Atherosclerosis and Coronary Artery Disease., 1 ed. Philadelphia: Lippincott - Raven; 1996. p. 13-21.

  211. Kannel WB. Clinical misconceptions dispelled by epidemiological research. Circulation 1995;92:3350-60.

  212. Vasan RS, Benjamin EJ, Levy D. Prevalence, clinical features and prognosis of diastolic heart failure: An epidemiologic perspective. J Am Coll Cardiol 1995;26:1565-74.

  213. Kannel WB, D'Agostino RB, Belanger AJ. Concept of bridging the gap from youth to adulthood. Am.J.Med.Sci. 1995;310(suppl 1):S15-S21.

  214. Vasan RS, Larson MG, Benjamin EJ, Levy D. Echocardiographic reference values for aortic root size: The Framingham Heart Study. J Am Soc Echocardiogr 1995;8:793-800.

  215. Kannel WB. Blood pressure as a contributor to stroke. Federal Practitioner 1995;Supplement:14-20.

  216. Lauer MS, Okin PM, Anderson KM, Levy D. Impact of echocardiographic left ventricular mass on mechanistic implications of exercise testing parameters. Am J Cardiol 1995;76:952-56.

  217. Murabito JM, Larson MG, Lin ST, Evans JC, Levy D. Unexplained gradual-onset Q wave patterns. A case series from the Framingham Study. J Electrocardiol 1995;28:267-75.

  218. Kannel WB. Range of serum cholesterol values in the population developing coronary artery disease. Am J Cardiol 1995;76:69C-77C.

  219. Kannel WB, Wilson PWF. An update on coronary risk factors. Med Clin North Am 1995;79:951-71.

  220. Felson DT, Zhang Y, Hannan MT, Kannel WB, Kiel DP. Alcohol intake and bone mineral density in elderly men and women. Am J Epidemiol 1995;142:485-92.

  221. Vaziri SM, Larson MG, Lauer MS, Benjamin EJ, Levy D. Influence of blood pressure on left atrial size. The Framingham Heart Study. Hypertension 1995;25:1155-60.

  222. Gates GA, Popelka G. Neural presbycusis: a diagnostic dilemma. Am J Otol 1992;13:313-17.

  223. Cooper J, Gates GA. Hearing in the elderly - The Framingham cohort, 1983-1985: Part II. Prevalence of central auditory processing disorders. Ear Hear 1991;12:304-11.

  224. Gates GA, Cooper J. Incidence of hearing decline in the elderly. Acta Otolaryngol 1991;111:240-48.

  225. Roubenoff R, Dallal G, Wilson PWF. Predicting body fatness: the body mass index vs estimation by bioelectrical impedance. Am J Public Health 1995;85:726-28.

  226. Lyu L, Posner BM, Shieh M, Lichtenstein AH, Cupples LA, Dwyer J et al. Cross-cultural comparisons between Taipei Chinese and Framingham Americans: dietary intakes, blood lipids and apolipoproteins. Asia Pacific J Clin Nutr 1994;3:119-25.

  227. Gillman MW, Cupples LA, Gagnon DR, Posner BM, Ellison R, Castelli WP et al. Protective effect of fruits and vegetables on development of stroke in men. JAMA 1995;273:1113-17.

  228. Krumholz H, Larson M, Levy D. Prognosis of left ventricular geometric patterns in the Framingham Heart Study. J Am Coll Cardiol 1995;25:879-84.

  229. Vasan R, Larson MG, Levy D. Determinants of echocardiographic aortic root size. The Framingham Heart Study. Circulation 1995;91:734-40.

  230. Kannel WB. Natural history of cardiovascular risk, In: Braunwald E, Hollenberg N, editors. Atlas of Heart Diseases. Hypertension: Mechanisms and Therapy, 1 ed. Philadelphia: Current Medicine; 1995.

  231. Kannel WB. Coronary risk factors: an overview, In: Willerson J, Cohn J, editors. Cardiovascular Medicine. New York: Churchill Livingstone, Inc.; 1995. p. 1809-28.

  232. Kannel WB, Wilson PWF. Risk factors that attenuate the female coronary disease advantage. Arch Intern Med 1995;155:57-61.

  233. Selhub J, Jacques PF, Bostom AG, D'Agostino RB, Wilson PWF, Belanger AJ et al. Association between plasma homocysteine concentrations and extracranial carotid-artery stenosis. N Engl J Med 1995;332:286-91.

  234. Lindenbaum J, Rosenberg IH, Wilson PWF, Stabler S, Allen R. Prevalence of cobalamin deficiency in the Framingham elderly population. Am J Clin Nutr 1994;60:2-11.

  235. Wilson PWF, Anderson KM, Harris T, Kannel WB, Castelli WP. Determinants of change in total cholesterol and HDL-C with age: the Framingham Study. J Gerontol 1994;49:M252-M257.

  236. Lyu L, Shieh M, Posner BM, Ordovas JM, Dwyer J, Lichtenstein AH et al. Relationship between dietary intake, lipoproteins, and apolipoproteins in Taipei and Framingham. Am J Clin Nutr 1994;60:765-74.

  237. D'Agostino RB, Kannel WB, Stepanians M, D'Agostino LC. Efficacy and tolerability of lovastatin in hypercholesterolemia in patients with systemic hypertension. Am J Cardiol 1993;71:82-87.

  238. Truelsen T, Lindenstrom E, Boysen G. Comparison of probability of stroke between the Copenhagen City Heart Study and the Framingham Study. Stroke 1994;25:802-07.

  239. Garrison RJ, Sawin CT, Alexander L, Wilson PWF. Plasma estradiol in premenopausal women: the Framingham Offspring Study. Journal of Women's Health 1994;3:435-43.

  240. Sherman S.E., D'Agostino RB, Cobb JL, Kannel WB. Physical activity and mortality in women in the Framingham Heart Study. Am Heart J 1994;128:879-84.

  241. Wilson PWF, Myers RH, Larson MG, Ordovas JM, Wolf PA, Schaefer EJ. Apolipoprotein E alleles, dyslipidemia, and coronary heart disease. The Framingham Offspring Study. JAMA 1994;272:1666-71.

  242. Vaziri SM, Larson MG, Benjamin EJ, Levy D. Echocardiographic predictors of nonrheumatic atrial fibrillation. The Framingham Heart Study. Circulation 1994;89:724-30.

  243. Benjamin EJ, Levy D, Vaziri SM, D'Agostino RB, Belanger AJ, Wolf PA. Independent risk factors for atrial fibrillation in a population- based cohort. The Framingham Heart Study. JAMA 1994;271:840-44.

  244. Krumholz HM, Larson M, Levy D. Sex differences in cardiac adaptation to isolated systolic hypertension. Am J Cardiol 1993;72:310-13.

  245. Hannan MT, Anderson JJ, Zhang Y, Levy D, Felson DT. Bone mineral density and knee osteoarthritis in elderly men and women. The Framingham Study. Arthritis Rheum 1993;36:1671-80.

  246. Bikkina M, Larson MG, Levy D. Asymptomatic ventricular arrhythmias and mortality risk in subjects with left ventricular hypertrophy. J Am Coll Cardiol 1993;22:1111-16.

  247. Levy D. A multifactorial approach to coronary disease risk assessment. Clin Exp Hypertens 1993;15:1077-86.

  248. Sagie A, Benjamin EJ, Galderisi M, Larson MG, Evans JC, Fuller DL et al. Echocardiographic assessment of left ventricular structure and diastolic filling in elderly subjects with borderline isolated systolic hypertension (the Framingham Heart Study). Am J Cardiol 1993;72:662-65.

  249. Sagie A, Larson MG, Goldberg RJ, Bengtson JR, Levy D. An improved method for adjusting the QT interval for heart rate (the Framingham Heart Study). Am J Cardiol 1992;70:797-801.

  250. Kannam JP, Levy D, Larson M, Wilson PWF. Short stature and risk for mortality and cardiovascular disease events. Circulation 1994;90:2241-47.

  251. Post WS, Larson MG, Levy D. Hemodynamic predictors of incident hypertension: the Framingham Heart Study. Hypertension 1994;24:585-90.

  252. Levy D, Salomon M, D'Agostino RB, Belanger AJ, Kannel WB. Prognostic implications of baseline electrocardiographic features and their serial changes in subjects with left ventricular hypertrophy. Circulation 1994;90:1786-93.

  253. Ordovas JM, Civeira F, Genest JJ, Craig S, Robbins AH, Meade T et al. Restriction fragment length polymorphism of the apolipoprotein A- I, C-III, A-IV gene locus Relationships with lipids, apolipoproteins, and premature coronary artery disease. Atherosclerosis 1991;87:75-86.

  254. Castelli WP. Section A: untoward associations of low serum cholesterol levels. Long-term relationship between serum cholesterol and total mortality in the Framingham Heart Study, In: Lewis B, Paoletti R, Tikkanen MJ, editors. Low Blood Cholesterol: Health Implications. Proceedings of the International Task Force for the Prevention of Coronary Heart Disease and the International Society and Federation of Cardiology. London: Current Medical Literature Ltd.; 1993. p. 2-9.

  255. Sawin CT, Geller A, Wolf PA, Belanger AJ, Baker E, Bacharach P et al. Low serum thyrotropin concentrations as a risk factor for atrial fibrillation in older persons. N Engl J Med 1994;331:1249-52.

  256. Gebara C, Mittleman M, Sutherland P, Lipinska I, Matheney T, Xu P et al. Association between increased estrogen status and increased fibrinolytic potential in the Framingham Offspring Study. Circulation 1995;91:1952-58.

  257. Kiely DK, Wolf PA, Cupples LA, Beiser AS, Kannel WB. Physical activity and stroke risk: the Framingham Study. Am J Epidemiol 1994;140:608-20.

  258. Schaefer EJ, Lamon-Fava S, Ordovas JM, Cohn SD, Schaefer MM, Castelli WP et al. Factors associated with low and elevated plasma high density lipoprotein cholesterol and apolipoprotein A-1 levels in the Framingham Offspring Study. J Lipid Res 1994;35:871-82.

  259. Schaefer EJ, Lamon-Fava S, Cohn SD, Schaefer MM, Ordovas JM, Castelli WP et al. Effects of age, gender, and menopausal status on plasma low density lipoprotein cholesterol and apolipoprotein B levels in the Framingham Offspring Study. J Lipid Res 1994;35:779-92.

  260. The Framingham Offspring Eye Study Group. Familial aggregation of lens opacities: the Framingham Eye Study and the Framingham Offspring Eye Study. Am J Epidemiol 1994;140:555-64.

  261. Kreger BE, Odell PM, D'Agostino RB, Wilson PWF. Long-term intraindividual cholesterol variability: Natural course and adverse impact on morbidity and mortality--the Framingham Study. Am Heart J 1994;127:1607-14.

  262. Wilson PWF. Established risk factors and coronary artery disease: the Framingham Study. Am J Hypertens 1994;7:7s-12s.

  263. Wilson PWF, Larson MG, Castelli WP. Triglycerides, HDL cholesterol and coronary artery disease: a Framingham update on their interrelations. Can J Cardiol 1994;10:5b-9b.

  264. Kannel WB, Levy D, Cupples LA. Left ventricular hypertrophy and risk of cardiac failure: Insights from the Framingham Study. J Cardiovasc Pharmacol 1987;10(Suppl6):S135-S140.

  265. Schaefer EJ, Lamon-Fava S, Johnson S, Ordovas JM, Schaefer MM, Castelli WP et al. Effects of gender and menopausal status on the association of apolipoprotein E phenotype with plasma lipoprotein levels: results from the Framingham Offspring Study. Arterioscler Tromb 1994;14:1105-13.

  266. Bostom AG, Gagnon DR, Cupples LA, Wilson PWF, Jenner JL, Ordovas JM. A prospective investigation of elevated lipoprotein (a) detected by electrophoresis and cardiovascular disease in women: the Framingham Heart Study. Circulation 1994;90:1688-95.

  267. Tsuji H, Venditti FJ, Evans JC, Larson MG, Levy D. The associations of levels of serum potassium and magnesium with ventricular premature complexes (the Framingham Heart Study). Am J Cardiol 1994;74:232-35.

  268. Tsuji H, Venditti FJ, Manders ES, Evans JC, Larson MG, Feldman CL et al. Reduced heart rate variability and mortality risk in an elderly cohort: the Framingham Heart Study. Circulation 1994;90:878-83.

  269. Post WS, Larson MG, Levy D. Impact of left ventricular structure on the incidence of hypertension: the Framingham Heart Study. Circulation 1994;90:179-85.

  270. Kannel WB, Thom T. Incidence, prevalence, and mortality of cardiovascular diseases, In: Schlant RC, Alexander RW, O'Rourke RA, Roberts R, Sonnenblick EH, editors. Hurst's the Heart. New York: McGraw-Hill; 1994. p. 185-97.

  271. Kannel WB. Rationale for treatment of hypertension in the elderly. American Journal of Geriatric Cardiology 1994;33-45.

  272. Kannel WB, Ho KKL, Thom T. Changing epidemiological features of cardiac failure. Br Heart J 1994;72(Suppl).

  273. Guccione AA, Felson DT, Anderson JJ, Anthony JM, Zhang Y, Wilson PWF et al. The effects of specific medical conditions on the functional limitations of elders in the Framingham Study. Am J Public Health 1994;84:351-58.

  274. Lauer MS, Anderson KM, Larson MG, Levy D. A new method for indexing left ventricular mass for differences in body size. Am J Cardiol 1994;74:487-91.

  275. Kannel WB, Wilson PWF. Efficacy of lipid profiles in prediction of coronary desease. Am Heart J 1992;768-74.

  276. Civeira F, Genest JJ, Pocovi M, Salem DN, Herbert PN, Wilson PWF. The MspI restriction fragment length polymorphism 3' to the apolipoprotein A-II gene: relationships with lipids, apolipoproteins, and premature coronary artery disease. Atherosclerosis 1992;92:165-76.

  277. Post WS, Levy D. New developments in the epidemiology of left ventricular hypertrophy. Current Opinion in Cardiology 1994;9:534-41.

  278. Campos H, Willett WC, Peterson RM, Siles X, Bailey SM, Wilson PWF et al. Nutrient intake comparisons between Framingham and rural and urban Puriscal, Costa Rica. Arterioscler Tromb 1991;11:1089-99.

  279. Anderson KM, Dumphy D, Wilson PWF. Management of data quality in a long-term epidemiologic study: the Framingham Heart Study, In: Liepins GE, Uppuluri VRR, editors. Data Quality Control Theory and Pragmatics. New York: Marcel Dekker, Inc.; 1990. p. 57-68.

  280. Wilson PWF, Kannel WB. Epidemiology of hyperglycemia and atherosclerosis, In: Ruderman N, editor. Hyperglycemia, Diabetes, and Vascular Disease. New York: Oxford University Press; 1992. p. 21-29.

  281. Wilson PWF, Anderson KM, Castelli WP. The impact of triglycerides on coronary heart disease: the Framingham Study, In: Gotto AM, Paoletti R, editors. Atherosclerosis Review. New York: Ravin Press; 1991. p. 59-63.

  282. Genest JJ, Jenner JL, McNamara JR, Ordovas JM, Silberman SR, Wilson PWF et al. Prevalence of lipoprotein (a) [Lp(a)] excess in coronary artery disease. Am J Cardiol 1991;67:1039-45.

  283. Genest JJ, Bard JM, Fruchart JC, Ordovas JM, Wilson PWF, Schaefer EJ. Plasma apolipoprotein A-I, A-II, B, E and C-III containing particles in men with premature coronary artery disease. Atherosclerosis 1990;149-57.

  284. Felson DT, Hannan MT, Naimark A, Berkeley J, Gordon G, Wilson PWF et al. Occupational physical demands, knee bending, and knee osteoarthritis: results from the Framingham Study. J Rheumatol 1991;18:1587-92.

  285. Wilson PWF, Anderson KM. Hdl cholesterol and triglycerides as risk factors for chd, In: Gaddi DA, Lenzi M, Lenzi S, editors. Atherosclerosis and Cardiovascular Disease. Dordrecht: Kluwer academic publishers; 1990. p. 609-15.

  286. Wilson PWF, Castelli WP. Coronary heart disease: the view from Framingham, In: Shepherd J, editor. Coronary Risk Factors Revisited. Dublin: Elsevier Science Publishers B.V.; 1989. p. 3-14.

  287. Kannel WB. Epidemiology of hypertension with concomitant metabolic disorders, In: Kaplan NM, editor. Metabolic Aspects of Hypertension. London: Science Press Ltd; 1994. p. 1.1-1.13.

  288. Posner BM, Cupples LA, Franz MM, Gagnon DR. Diet and heart disease risk factors in adult American men and women: the Framingham Offspring-Spouse Nutrition Studies. Int J Epidemiol 1993;22:1014-25.

  289. Gagnon DR, Zhang T, Brand FN, Kannel WB. Hematocrit and the risk of cardiovascular disease-the Framingham Study: a 34-year follow-up. Am Heart J 1994;127:674-82.

  290. Bikkina M, Levy D, Evans JC, Larson MG, Benjamin EJ, Wolf PA et al. Left ventricular mass and risk of stroke in an elderly cohort. JAMA 1994;272:33-36.

  291. Campos H, Genest JJ, Blijlevens E, McNamara JR, Jenner JL, Wilson PWF et al. Low density lipoprotein particle size and coronary artery disease. Arterioscler Tromb 1992;12:187-95.

  292. Kannel WB, D'Agostino RB, Stepanians M, D'Agostino LC. Efficacy and tolerability of lovastatin in a six-month study: analysis by gender, age and hypertensive status. Am J Cardiol 1990;66:1B-10B.

  293. Schauffler HH, D'Agostino RB, Kannel WB. The elderly and associated medicare costs: the Framingham Study. Am J Prev Med 1993;9:146-54.

  294. Sagie A, Benjamin EJ, Galderisi M, Larson MG, Evans JC, Fuller DL et al. Reference values for doppler indexes of left ventricular diastolic filling in the elderly. J Am Soc Echocardiogr 1993;6:570-76.

  295. Vaziri SM, Evans JC, Larson MG, Wilson PWF. The impact of female hormone usage on the lipid profile the Framingham Offspring Study. Arch Intern Med 1993;153:2200-06.

  296. Jenner JL, Ordovas JM, Lamon-Fava S, Schaefer MM, Wilson PWF. Effects of age, sex, and menopausal status on plasma lipoprotein(a) levels the Framingham Offspring Study. Circulation 1993;87:1135-41.

  297. Roubenoff R, Wilson PWF. Advantage of knee height over height as an index of stature in expression of body composition in adults. Am J Clin Nutr 1993;57:609-13.

  298. Felson DT, Zhang Y, Hannan MT, Kiel DP, Wilson PWF, Anderson JJ. The effect of postmenopausal estrogen therapy on bone density in elderly women. N Engl J Med 1993;329:1141-46.

  299. Sagie A, Larson MG, Levy D. The natural history of borderline isolated systolic hypertension. N Engl J Med 1993;329:1912-17.

  300. Murabito JM, Evans JC, Larson MG, Levy D. Prognosis after the onset of coronary heart disease. Circulation 1993;88:2548-55.

  301. Shively CA, Knox SS, Sherwin BB, Walsh BW, Wilson PWF. Sex steroids, psychosocial factors, and lipid metabolism. Metabolism 1993;42:9:(Suppl 1):16-24.

  302. Selhub J, Jacques PF, Wilson PWF, Rush D, Rosenberg IH. Vitamin status and intake as primary determinants of homocysteinemia in an elderly population. JAMA 1993;270:2693-98.

  303. Wilson PWF, Kannel WB. Hypercholesterolemia and coronary risk in the elderly: the Framingham Study. American Journal of Geriatric Cardiology 1993;52-56.

  304. Kannel WB. Hypertension as a risk factor for cardiac events--epidemiologic results of long-term studies. J Cardiovasc Pharmacol 1993;21:(Suppl 2):S27-S37.

  305. Kannel WB. Multivariate cardiovascular risk assessment. J Myocard Ischemia 1993;5(Suppl 1):30-35.

  306. Genest JJ, Martin-Munley SS, McNamara JR, Ordovas JM, Jenner J, Myers RH et al. Familial lipoprotein disorders in patients with premature coronary artery disease. Circulation 1992;85:2025-33.

  307. Campos H, Blijlevens E, McNamara JR, Ordovas JM, Posner BM, Wilson PWF et al. LDL particle size distribution: Results from the Framingham Offspring Study. Arterioscler Tromb 1992;12:1410-19.

  308. Kannel WB. Individual risk factors for cardiovascular disease, In: Gotto AM, Lenfant C, Paoletti R, Soma M, editors. Multiple Risk Factors in Cardiovascular Disease. Dordrecht: Kluwer Academic; 1992. p. 1-12.

  309. Galderisi M, Benjamin EJ, Evans JC, D'Agostino RB, Fuller DL, Lehman B et al. Impact of heart rate and pr interval on doppler indexes of left ventricular diastolic filling in an elderly cohort (the Framingham Heart Study). Am J Cardiol 1993;72:1183-87.

  310. Cobb JL, D'Agostino RB. Norms for the mini-mental state examination. JAMA 1993;270:2178.

  311. Castelli WP. Concerning the possibility of a nut...(editorial). Arch Intern Med 1992;152:1371.

  312. Posner BM, Smigelski C, Duggal A, Morgan JL, Cobb J, Cupples LA. Validation of two-dimensional models for estimation of portion size in nutrition research. J Am Diet Assoc 1992;92:738-41.

  313. Sonnenberg LM, Posner BM, Belanger AJ, Cupples LA, D'Agostino RB. Dietary predictors of serum cholesterol in men: the Framingham cohort population. J Clin Epidemiol 1992;45:413-18.

  314. D'Agostino RB. Discussion of papers of session 2: incomplete, multivariate, non- linear. Stat Med 1992;11:1955-63.

  315. Posner BM, Cupples LA, Miller DR, Cobb JL, Lutz KJ, D'Agostino RB. Diet, menopause, and serum cholesterol levels in women: the Framingham Study. Am Heart J 1993;125:2:Part 1:483-89.

  316. Posner BM, Cupples LA, Gagnon DR, Wilson PWF, Chetwynd K, Felix D. Healthy people 2000: the rationale and potential efficacy of preventive nutrition in heart disease: the Framingham Offspring- Spouse Study. Arch Intern Med 1993;153:1549-56.

  317. Bachman DL, Wolf PA, Linn RT, Knoefel JE, Cobb JL, Belanger AJ et al. Incidence of dementia and probable Alzheimer's disease in a general population: the Framingham Study. Neurology 1993;43:515-19.

  318. Hathaway DK, D'Agostino RB. A technique for summarizing longitudinal data. Stat Med 1993;12:2169-78.

  319. Gates GA, Cobb JL, D'Agostino RB, Wolf PA. The relation of hearing in the elderly to the presence of cardiovascular disease and cardiovascular risk factors. Arch Otolaryngol 1993;119:156-61.

  320. Kannel WB, D'Agostino RB, Belanger AJ. Update on fibrinogen as a cardiovascular risk factor. Ann Epidemiol 1992;2:457-66.

  321. Kannel WB, Cobb J. Left Ventricular hypertrophy and mortality-results from the Framingham Study. Cardiology 1992;81:291-98.

  322. Cupples LA, Gagnon DR, Wong ND, Ostfeld AM, Kannel WB. Preexisting cardiovascular conditions and long-term prognosis after initial myocardial infarction: the Framingham Study. Am Heart J 1993;125:863-72.

  323. Singer DE, Nathan DM, Anderson KM, Wilson PWF, Evans JC. Association of hba1c with prevalent cardiovascular disease in the original cohort of the Framingham Heart Study. Diabetes 1992;41:202-08.

  324. Galderisi M, Lauer MS, Levy D. Echocardiographic determinants of clinical outcome in subjects with coronary artery disease (the Framingham Heart Study). Am J Cardiol 1992;70:971-76.

  325. Galderisi M, Benjamin EJ, Evans JC, D'Agostino RB, Fuller DL, Lehman B et al. Intra- and interobserver reproducibility of doppler-assessed indexes of left ventricular diastolic function in a population- based study (the Framingham Heart Study). Am J Cardiol 1992;70:1341-46.

  326. Lauer MS, Evans JC, Levy D. Prognostic implications of subclinical left ventricular dilation and systolic dysfunction in men free of overt cardiovascular disease (the Framingham Heart Study). Am J Cardiol 1992;70:1180-84.

  327. Bikkina M, Larson MG, Levy D. Prognostic implications of asymptomatic ventricular arrhythmias: the Framingham Study. Ann Intern Med 1992;117:990-96.

  328. Castelli WP. The fact and fiction of lowering cholesterol concentrations in the primary prevention of coronary heart disease. Br Heart J 1993;69(Supplement):s70-s73.

  329. Castelli WP. Epidemiology of triglycerides: a view from Framingham. Am J Cardiol 1993;70:3h-9h.

  330. Ho KKL, Pinsky JL, Levy D. The epidemiology of heart failure: the Framingham Study. J Am Coll Cardiol 1993;22:4(Suppl A):6a-13a.

  331. Kannel WB. Potency of vascular risk factors as the basis for antihypertensive therapy. Eur Heart J 1992;13(supplement G):34-42.

  332. Kannel WB. Hypertension in the elderly: epidemiologic appraisal from the Framingham Study. Cardiology in the Elderly 1993;1:359-63.

  333. Ho KKL, Anderson KM, Kannel WB, Grossman W, Levy D. Survival after the onset of congestive heart failure in Framingham Heart Study subjects. Circulation 1993;88:107-15.

  334. Norman JE, Levy D, Campbell G, Bailey JJ. Improved detection of echocardiographic left ventricular hypertrophy using a new electrocardiographic algorithm. J Am Coll Cardiol 1993;21:1680-86.

  335. Kannel WB, Garrison RJ, Dannenberg AL. Secular blood pressure trends in normotensive persons: the Framingham Study. Am Heart J 1993;125:1154-58.

  336. Garrison RJ. Healthy adiposity in women: the Framingham Offspring Study. J Am Coll Nutr 1993;12:357-62.

  337. Garrison RJ, Kannel WB. A new approach for estimating healthy body weights. Int J Obes 1993;17:417-23.

  338. Wolf PA, Belanger AJ, D'Agostino RB. Quantifying stroke risk factors and potentials form risk reduction. Cerebrovasc Dis 1993;3(suppl 1):7-14.

  339. Wolf PA, D'Agostino RB. Secular trends in stroke in the Framingham Study. Ann Epidemiol 1993;3:471-75.

  340. Gillman MW, Kannel WB, Belanger A, D'Agostino RB. Influence of heart rate on mortality among persons with hypertension: the Framingham Study. Am Heart J 1993;125:1148-54.

  341. Odell PM, Anderson KM, D'Agostino RB. Maximun likelihood estimation for interval-censored data using a Weibull-based accelerated failure time model. Biometrics 1992;48:951-59.

  342. Markovitz JH, Matthews KA, Kannel WB, Cobb JL, D'Agostino RB. Psychological predictors of hypertension in the Framingham Study.Is there tension in hypertension? JAMA 1993;270:2439-43.

  343. Ness RB, Harris T, Cobb J, Flegal KM, Kelsey JL, Balanger A et al. Number of pregnancies and the subsequent risk of cardiovascular disease. N Engl J Med 1993;328:1528-33.

  344. Elias MF, Wolf PA, D'Agostino RB, Cobb J, White LR. Untreated blood pressure level is inversely related to cognitive functioning: the Framingham Study. Am J Epidemiol 1993;138:353-63.

  345. Higgins M, D'Agostino R, Kannel W, Cobb J. Benefits and adverse effects of weight loss. Observations from the Framingham Study. Ann Intern Med 1993;119:758-63.

  346. Lyu L, Shieh M, Ordovas JM, Lichtenstein AH, Wilson PWF, Schaefer EJ. Plasma lipoprotein and apolipoprotein levels in Taipei and Framingham. Arterioscler Tromb 1993;13:1429-40.

  347. Garrison RJ, Gold RS, Wilson PWF, Kannel WB. Educational attainment and coronary heart disease risk: the Framingham Offspring Study. Prev.Med. 1993;22:54-64.

  348. Wolf PA, D'Agostino RB, O'Neal MA, Sytkowski PA, Kase CS, Belanger AJ et al. Secular trends in stroke incidence and mortality. The Framingham Study. Stroke 1992;23:1551-55.

  349. Kannel WB. Fibrinogen: a major cardiovascular risk factor, In: Ernst E, Koenig W, Lowe GDO, Meade TW, editors. Fibrinogen: A "New" Cardiovascular Risk Factor. Austria: Blackwell-MZV; 1992. p. 101-09.

  350. Kannel WB. Atherogenic lipid profiles: office assessment, In: Kastelein JJP, editor. Clinical Issues in Hyperlipidaemia, 1 ed. Netherlands: Reed Healthcare Communications; 1992.

  351. Kannel WB. Left ventricular hypertrophy as a risk factor in arterial hypertension. Eur.Heart J. 1992;13,Suppl D:82-88.

  352. Kannel WB. Epidemiological implications of left ventricular hypertrophy, In: Cruickshank JM, Messerli FH, editors. Left Ventricular Hypertrophy and its Regression. London: Science Press; 1992. p. 1-11.

  353. Kannel WB. Aspects of therapeutics (4):office assessment of coronary candidates. J Drug Dev 1992;5:49-58.

  354. Kannel WB. Low high-density lipoprotein cholesterol and what to do about it. Am.J.Cardiol. 1992;70:810-14.

  355. D'Agostino RB, Kannel WB, Stepanians MN, D'Agostino LC. Efficacy and tolerability of lovastatin in hypercholesterolemic women. Clin Ther 1992;14:390-95.

  356. Kannel WB. The Framingham experience, In: Marmot M, Elliott P, editors. Coronary Heart Disease Epidemiology:from Aetiology to Public Health. New York: Oxford University Press; 1992. p. 67-82.

  357. Kreger BE, Anderson KM, Schatzkin A, Splansky GL. Serum cholesterol level, body mass index, and the risk of colon cancer. Cancer 1992;70:1038-43.

  358. Benjamin EJ, Levy D, Anderson KM, Wolf PA, Plehn JF, Evans JC et al. Determinates of Doppler indexes of left ventricular diastolic function in normal subjects (the Framingham Heart Study). Am.J.Cardiol. 1992;70:508-15.

  359. Berger JM, Murabito JM, Evans JC, Anderson KM, Levy D. Prognosis after first myocardial infarction. Comparison of Q-wave and non-Q-wave myocardial infarction in the Framingham Heart Study. JAMA 1992;268:1545-51.

  360. Benjamin EJ, Plehn JF, D'Agostino RB, Belanger AJ, Comai K, Fuller DL et al. Mitral annular calcification and the risk of stroke in an elderly cohort. N.Engl.J.Med. 1992;327:374-79.

  361. Brand FN, Kiely D, Kannel WB, Myers RH. Family patterns of coronary heart disease mortality: the Framingham Longevity Study. J.Clin.Epidemiol. 1992;45:169-74.

  362. Kannel WB, Anderson KM, Evans JC. Relevance of blood lipids in the elderly: the Framingham Study. Cardiovascular Risk Factors 1992;170-79.

  363. Kannel WB. CV risk factor assessment in the elderly. Geriatric Consultant 1992;14-16.

  364. Castelli WP, Anderson KM, Wilson PWF, Levy D. Lipids and risk of coronary heart disease. The Framingham Study. Ann Epidemiol 1992;2:23-28.

  365. Kannel WB. Epidemiology of cardiovascular disease in the elderly: an assessment of risk factors., In: Lowenthal DT, Brest AN, editors. Geriatric Cardiology. Philadelphia: F.A. Davis; 1992. p. 9-22.

  366. Freund KM, D'Agostino RB, Belanger AJ, Kannel WB, Stokes JI. Predictors of smoking cessation: the Framingham Study. Am.J.Epidemiol. 1992;135:957-64.

  367. Kelly-Hayes M, Jette AM, Wolf PA, D'Agostino RB, Odell PM. Functional limitations and disability among elders in the Framingham Study. Am.J.Public Health 1992;82(6):841-45.

  368. Eaker ED, Pinsky JL, Castelli WP. Myocardial infarction and coronary death among women: psychosocial predictors from a 20 year follow-up of women in the Framingham Study. Am.J.Epidemiol. 1992;135(8):854-64.

  369. Wolf PA, Belanger AJ, D'Agostino RB. Management of risk factors, In: Barnett HJM, Hachinski VC, editors. Neurologic Clinics. Philadelphia: Harcourt Brace Jovanovich,Inc.; 1992. p. 177-91.

  370. Weldon B. Weight loss reduces the risk of osteoarthritis of the knee. The NIH Record 1992;XLIV(10):3.

  371. Posner BM, Martin-Munley SS, Smigelski C, Cupples LA, Cobb JL, Schaefer EJ et al. Comparison of techniques for estimating nutrient intake: the Framingham Study. Epidemiology 1992;3:171-77.

  372. Levy D, Murabito JM, Anderson KM, Christiansen JC, Castelli WP. Echocardiographic left ventricular hypertrophy: clinical characteristics. The Framingham Heart Study. Clin Exp Hypertens [A] 1992;14(1-2):85-97.

  373. Lauer MS, Levy D, Anderson KM, Plehn JF. Is there a relationship between exercise systolic blood pressure response and left ventricular mass? The Framingham Heart Study. Ann.Intern.Med. 1992;116(3):203-10.

  374. Lauer MS, Anderson KM, Levy D. Separate and joint influences of obesity and mild hypertension on left ventricular mass and geometry: the Framingham Heart Study. JACC 1992;19(1):130-34.

  375. Kannel WB, Wolf PA. Pulling it all together: Changing the cardiovascular outlook. Am.Heart J. 1992;123:1:264-67.

  376. Kannel WB, Anderson KM, Wilson PWF. White blood cell count and cardiovascular disease. JAMA 1992;267:9:1253-56.

  377. Kannel WB, Vokonas PS. Demographics of the prevalence, incidence, and management of coronary heart disease in the elderly and in women. Ann Epidemiol 1992;2:112:5-14.

  378. Kannel WB, Wolf PA. Epidemiology of atrial fibrillation, In: Falk RH, Podrid PJ, editors. Atrial Fibrillation: Mechanisms and Management. New York: Raven Press, Ltd.; 1992. p. 81-92.

  379. Genest JJ, McNamara JR, Ordovas JM, Jenner JL, Silberman SR, Anderson KM et al. Lipoprotein cholesterol, apolipoprotein A-I and B and lipoprotein (a) abnormalities in men with premature coronary artery disease. JACC 1992;19(4):792-802.

  380. Felson DT, Zhang Y, Anthony JM, Naimark A, Anderson JJ. Weight loss reduces the risk for symptomatic knee osteoarthritis in women. The Framingham Study [see comments]. Ann.Intern.Med. 1992;116(7):535-39.

  381. Feinleib M, Pinsky JL. Nonrandom attrition in the Framingham Heart Study, In: Dwyer JH, Feinleib M, Lippert P, Hoffmeister H, editors. Statistical Models for Longitudinal Studies of Health, 16 ed. New York: Oxford University Press; 1992. p. 251-76.

  382. D'Agostino RB, Cobb JL, Wolf PA, Wilson PWF. Aspirin use and cardiovascular disease in women. JAMA 1992;267:3:264-365.

  383. Cupples LA, Gagnon DR, Kannel WB. Long and short-term risk of sudden coronary death. Circulation 1992;85:1(Suppl I):I11-I18.

  384. Bachman DL, Wolf PA, Linn R, Knoefel JE, Cobb JC, Belanger A et al. Prevalence of dementia and probable senile dementia of the alzheimer type in the Framingham Study. Neurology 1992;42:115-19.

  385. Wong ND, Wilson PWF, Kannel WB. Serum cholesterol as a prognostic factor after myocardial infarction: the Framingham Study. Ann.Intern.Med. 1991;115:687-93.

  386. Wolf PA, Abbott RD, Kannel WB. Atrial fibrillation as an independent risk factor for stroke: the Framingham Study. Stroke 1991;22:8:983-88.

  387. Wolf PA, D'Agostino RB, Belanger AJ, Kannel WB. Probability of stroke: A risk profile from the Framingham Study. Stroke 1991;22:3:312-18.

  388. Wilson PWF, Cupples LA, Kannel WB. Is hyperglycemia associated with cardiovascular disease? The Framingham Study. Am.J.Med. 1991;121 (2 Pt 1):586-90.

  389. Wilson PWF, Anderson KM, Castelli WP. Twelve-year incidence of coronary heart disease in middle-aged adults during the era of hypertensive therapy: the Framingham Offspring Study. Am.J.Med. 1991;90:11-16.

  390. Vokonas PS, Kannel WB. Hypertension in the elderly. Choices in Cardiology 1991;5:46-48.

  391. Sawin CT, Geller A, Kaplan MM, Bacharach P, Wilson PWF, Hershman JM. Low serum thyrotropin (thyroid-stimulating hormone) in older persons without hyperthyroidism. Arch.Intern.Med. 1991;151:165-68.

  392. Posner BM, Cobb JL, Belanger AJ, Cupples AC, D'Agostino RB, Stokes JI. Dietary lipid predictors of coronary heart disease in men. Arch.Intern.Med. 1991;151:1181-87.

  393. Okin PM, Anderson KM, Levy D, Kligfield P. Heart rate adjustment of exercise-induced ST segment depression. Improved risk stratification in the Framingham Study [see comments]. Circulation 1991;83(3):866-74.

  394. Manolio TA, Levy D, Garrison RJ, Castelli WP, Kannel WB. Relation of alcohol intake to left ventricular mass: the Framingham Study. JACC 1991;17:3:717-21.

  395. Lissner L, Odell PM, D'Agostino RB, Stokes JI, Kreger BE, Belanger AJ et al. Variability of body weight and health outcomes in the Framingham population. N.Engl.J.Med. 1991;324:26:1839-44.

  396. Levy D. Clinical significance of left ventricular hypertrophy: insights from the Framingham Study. J.Cardiovasc.Pharmacol. 1991;17 Suppl 2:S1-S6.

  397. Leitschuh M, Cupples LA, Kannel WB, Gagnon DR, Chobanian A. High-normal blood pressure progression to hypertension in the Framingham Heart Study. Hypertension 1991;17:1:22-27.

  398. Lauer MS, Anderson KM, Levy D. Influence of contemporary versus 30-year blood pressure levels on left ventricular mass and geometry: the Framingham Heart Study [see comments]. JACC 1991;18(5):1287-96.

  399. Lauer MS, Anderson KM, Kannel WB, Levy D. The impact of obesity on left ventricular mass and geometry. JAMA 1991;266:2:231-36.

  400. Kreger BE, Anderson KM, Levy D. QRS interval fails to predict coronary disease incidence. The Framingham Study. Arch.Intern.Med. 1991;151(7):1365-68.

  401. Kreger BE, Splansky GL, Schatzkin A. The cancer experience in the Framingham Heart Study cohort. Cancer 1991;67:1-6.

  402. Kannel WB. Hypertension, hypertrophy, and the occurrence of cardiovascular disease. Am.J.Med.Sci. 1991;302(4):199-204.

  403. Kannel WB, Wolf PA. The significance of cartoid bruits. Stroke 1991;22(2):283-84.

  404. Kannel WB. The clinical heterogeneity of hypertension. Am.J.Hypertens. 1991;4:283-87.

  405. Kannel WB, Cupples LA, Ramaswamy R, Stokes JI, Kreger BE, Higgins MW. Regional obesity and risk of cardiovascular disease; the Framingham Study. J.Clin.Epidemiol. 1991;44(2):183-90.

  406. Kannel WB. Left ventricular hypertrophy as a risk factor: the Framingham experience. J.Hypertens.Suppl. 1991;9(2):S3-S8.

  407. Kannel WB. Office assessment of coronary candidates and risk factor insights from the Framingham experience. J.Hypertens.Suppl. 1991;9(7):S13-S19.

  408. Kannel WB. Using a coronary risk profile in office evaluations. The Journal of Myocardial Ischemia 1991;3:5:70-78.

  409. Kannel WB. Epidemiology of essential hypertension: the Framingham experience. Proc.R.Coll.Physicians Edinb. 1991;21:273-87.

  410. Kannel WB, Belanger AJ. Epidemiology of heart failure. Am.Heart J. 1991;121:951-57.

  411. Kannel WB. Update on the role of cigarette smoking in coronary artery disease. Am.Heart J